Searchable abstracts of presentations at key conferences in endocrinology

ea0046p18 | (1) | UKINETS2016

High-grade neuroendocrine tumours of the oesophagus: a single centre experience

Salih Zena , Patrao Ana , Kordatou Zoe , Papaxoinis George , Mansoor Was

Background: High-grade neuroendocrine tumours (HGNETs) of the oesophagus are extremely rare and few cases have been reported worldwide. Here we aim to understand clinical profile, treatment strategy and outcomes for oesophageal HGNETs.Methods: We report a single-centre retrospective review of 21 patients with oesophageal HGNETs treated between 2011–2016. Data on incidence, tumour location, stage at presentation, histopathology, treatment protocol an...

ea0046p21 | (1) | UKINETS2016

Efficacy of the combination of Capecitabine and Temozolamide in patients with advanced Pulmonary Carcinoid Tumors: A single institution experience

Kordatou Zoe , Papaxoinis George , McCallum Lynn , Salih Zena , Nasralla Magdy , Nonaka Daisuke , Mansoor Wasat

Background: Pulmonary carcinoids (PC) are rare neuroendocrine tumors (NETs). The course of PCs is considered to be indolent, but patients with advanced disease have low survival rates and their treatment options are limited. As PCs are under-represented in trials, therapeutic decisions are based on evidence extrapolated from other types of NETS. Capecitabine-Temozolamide (CAPTEM) has demonstrated significant efficacy in pancreatic NETs. However, its role in PCs is still unexpl...

ea0046p2 | (1) | UKINETS2016

68Gallium-DOTANOC (68Ga-DOTANOC) positron emission tomography (PET) imaging in Bronchial Carcinoids (BC): multicentre evaluation of its role in clinical practice

Lamarca Angela , Pritchard D. Mark , Westwood Thomas , Papaxoinis George , Vinjamuri Sobhan , Valle Juan W , Manoharan Prakash , Mansoor Wasat

Background: New nuclear medicine imaging techniques have improved diagnosis, staging and treatment planning for BC. 68Ga-DOTA PET is preferable to standard somatostatin receptor scintigraphy where available (ENETS guidelines); however, its role in the management of BC remains unclear.Methods: All consecutive patients diagnosed with BC from two ENETS Centres of Excellence were identified retrospectively; patients with high grade tumours or lack...