Searchable abstracts of presentations at key conferences in endocrinology

ea0028p363 | Thyroid | SFEBES2012

The number of positive lymph nodes in the central compartment has no prognostic impact in papillary thyroid cancer

Parameswaran Rajeev , Sadler Gregory , Mihai Radu

Background: Papillary thyroid cancer (PTC) metastasizes to central compartment lymph nodes (CCLN) in majority of patients. Such metastases are associated with high risk of locoregional recurrence and distant metastasis. Only one study has investigated the relation between the number of metastatic CCLN and prognosis (Soon Lee et al. 2010 WJS). This study evaluated the clinical implication of the number of metastatic CCLN in PTC.Methods: Between Jan...

ea0025p73 | Clinical biochemistry | SFEBES2011

Introduction of day-case thyroid and parathyroid surgery has allowed achievement of the shortest length-of-stay in the United Kingdom

Parameswaran Rajeev , Sadler Gregory , Mihai Radu

Background: Length-of-stay (LOS) after various surgical procedures varies greatly between centres and countries. In the US there is increasing tendency towards day-case thyroid and parathyroid surgery but their model of care cannot be easily extrapolated. In the UK the average LOS for such operations is 3–4 days.Methods: Retrospective review of data retrieved from hospital-based software regarding the surgical activity during a decade in a large Uni...

ea0094p200 | Endocrine Cancer and Late Effects | SFEBES2023

SURvey of Surgeon’s and Physician’s experiences of GEnetic testing in patients with Familial Endocrine Syndromes: SurGe in UK and Abroad

de Jong Mechteld , Parameswaran Rajeev , Kurzawinski Tom

Introduction: Genetic testing for Familial Endocrine Syndromes has an important role in diagnosis, timing/extent of surgery, and follow-up. Our survey explored experiences and attitudes towards genetic testing in the UK and Abroad.Methods: Attendees of 2022 Conferences of ESES, BSPED, SfE, BAETS and AsianAES were asked to participate in an online survey (31 questions on demographics; genetic testing availability and expe...

ea0028p3 | Bone | SFEBES2012

Outcome of patients with negative neck exploration for primary hyperparathyroidism

Parameswaran Rajeev , Gleeson Fergus , Sadler Gregory , Mihai Radu

Background: Primary hyperparathyroidism (PHPT) is a common endocrine disease expected to be curable in 95% of patients undergoing surgical treatment. The aim of this study was to assess the postoperative course of patients with failed surgical treatment.Methods: Prospective database recorded clinical, biochemical, radiological, operative and pathological details of patients operated in a large tertiary referral centre.Results: Betw...

ea0021p212 | Endocrine tumours and neoplasia | SFEBES2009

Routine central compartment lymph node dissection for papillary thyroid cancer has minimal impact on early postoperative parameters

Parameswaran Rajeev , Stechman Michael , Weaver Andrew , Sadler Gregory , Mihai Radu

Background: Arguably patients undergoing total thyroidectomy for papillary thyroid cancers (PTC) are more likely to have negative radioactive iodine uptake and low/undetectable thyroglobulin levels if the central compartment lymph node dissection (CCLND) is performed routinely irrespective of the macroscopic appearance of the LN. The aim of this study was to determine whether routine CCLND leads to more favourable outcome in the first year after treatment for well-differentiat...

ea0031p366 | Thyroid | SFEBES2013

A rapidly enlarging neck lump and Horner's sign: lessons from a novel case

Donaldson James Fergus , Booth Frank , Parameswaran Rajeev , Rodriguez Gomez Iria Adriana

Background: Anaplastic carcinoma and primary lymphoma (TL) each constitute <2% of thyroid malignancies and are difficult to distinguish clinically. Both typically present with rapidly enlarging anterior neck masses in the elderly. Both may cause pressure symptoms (e.g. dysphagia, stridor and hoarseness). Differentiation is imperative as their treatment and prognoses differ.Case report: A 68-year-old man presented with a rapidly enlarging thyroid mass...

ea0094oc7.4 | Thyroid | SFEBES2023

The effectiveness of radioactive iodine vs thyroidectomy for paediatric grave’s disease: a systematic review and meta-analysis

He Shiyao George , Chia Li Ling Jolene , Pinto Diluka , Samuel Miny , Ho Cindy W.L. , Parameswaran Rajeev

Introduction: Definitive treatment for pediatric Grave’s disease includes radioiodine ablation (RAI) or thyroidectomy. The aim of this systematic review and meta-analysis was to compare the cure and relapse rates of RAI vs surgery as definitive therapy in children with Grave’s disease.Methods: A comprehensive search on Cochrane library, EMBASE, PUBMED and for English articles published on def...

ea0094p174 | Adrenal and Cardiovascular | SFEBES2023

Case series of catecholamine-induced Takotsubo cardiomyopathy secondary to pheochromocytoma and discussion of relevant literature

Lin Zhimin , Soh Bennet , Lee James , Yuan Ngiam Kee , Parameswaran Rajeev

Catecholamine-induced cardiomyopathy is a rare presentation of pheochromocytoma (PCC) with typical and atypical subtypes. These patients are associated with worse rates of morbidity and mortality compared to patients with PCC that were incidentally found. Frequently, these patients would present in the emergency setting with cardiac symptoms that may be difficult to distinguish from ischemic cardiomyopathy, and hence patients may be prescribed cardiac treatment in the form of ...

ea0094p176 | Adrenal and Cardiovascular | SFEBES2023

Current perceptions and practices by general practitioners (GPs) in the management of resistant hypertension

Wong Wai Kit Clement , Rui Lee , Leong Kwong Fei Eugene , Lee James , Pruar Troy , Parameswaran Rajeev

Introduction: About 12% of patients present to the GPs with hypertension or related symptoms. The current practice of managing resistant hypertension in primary care is inconsistent and general practitioners (GP’s) do not have a criteria for referral to tertiary care.Methods: Quantitative anonymized online survey of 26 questions on the current prescribing practices and thresholds for referral of resistant hypertensi...

ea0094p284 | Thyroid | SFEBES2023

Systematic review and meta-analysis (SRMA) of RAI monotherapy vs combination therapy for toxic nodular goiter (TMNG)

Huei-Sook Park Rachel , Tan Yi Rong Eugene , Pinto Diluka , Samuel Miny , Christine De Jong Mechteld , Parameswaran Rajeev

Background: Treatment options for patients with toxic multinodular goitre (TMNG) include antithyroid medications, thyroidectomy, and radioactive iodine (RAI) therapy. Our aim was to investigate the efficacy of RAI alone compared to combination therapy that includes RAI with medical therapy.Methods: Search was performed using MEDLINE, MEDLINE In-Process (PubMed platform), Embase (Elsevier platform), BIOSIS and Cochrane wa...