Searchable abstracts of presentations at key conferences in endocrinology

ea0081p407 | Pituitary and Neuroendocrinology | ECE2022

Endoscopic surgery for acromegaly: results and predictors of outcome from a 22-year experience of a referral Pituitary Centre

Guaraldi Federica , Zoli Matteo , Gori Davide , Cavicchi Riccardo , Pasquini Ernesto , Sollini Giacomo , Asioli Sofia , Mazzatenta Diego

Background: Endoscopic surgery (ES) performed in Pituitary Centers of Excellence (PCOE) represents the gold standard treatment for GH-secreting adenomas. However, rate of cure greatly varies according to definition criteria, follow-up duration, various patient and adenoma features, and surgeon ability.Study aim: To assess short- (3 month) and long-term (≥1 year) outcome and identify predictors of ES, in a large and homogeneous cohort of acromegaly ...

ea0032p850 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Endoscopic transsphenoidal approach as a promising surgical option in the treatment of craniopharyngioma

Faustini-Fustini Marco , Zoli Matteo , Mazzatenta Diego , Santi Daniele , Brigante Giulia , Pasquini Ernesto , Frank Giorgio

Introduction: The management of craniopharyngioma (CR) remains a challenge. The introduction of endoscopic technique in the surgical approach to the sellar/suprasellar region would have profound implications for treatment. The aim of the study was to analyze results, advantages and limits of endoscopic endonasal approach (EEA).Design/methods: From 1998 to 2012, 95 patients underwent surgery for CR. Trancranial approach was chosen for 33 patients (35%) on...

ea0022p665 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Transition from Cushing's disease to a hormonally inactive adenoma or vice versa: four unusual cases of corticotroph adenoma

Faustini-Fustini Marco , Zoli Matteo , Mazzatenta Diego , Pasquini Ernesto , Pia Foschini Maria , Granata Antonio , Frank Giorgio

Over the last decade 824 pituitary tumours have been removed in our centre. Of these, 114 (13.8%) were corticotroph adenomas. We present four unusual cases of corticotroph adenoma showing transition from Cushing’s disease to a hormonally inactive adenoma (case 1 and 2) or vice versa (case 3 and 4).Case 1: A 51-year-old man was admitted with a 2-year history of weight gain, arterial hypertension and chiasmatic syndrome. Cushing’s disease (CD) du...

ea0016p482 | Neuroendocrinology | ECE2008

Endoscopic pituitary surgery as the primary treatment for acromegaly: a prospective study in a specialised centre

Faustini-Fustini Marco , Magrini Satima , Anagni Mascia , Mazzatenta Diego , Pasquini Ernesto , Frank Giorgio

The main aims of treatment of acromegaly are reversing symptoms and signs, removing the tumour, preventing disease recurrence, and improving survival. Increased mortality associated with acromegaly can be diminished if treatment is successful in reducing GH <2–2.5 ng/ml. We carried out a prospective study to assess whether recent advances in surgical technique (namely the endoscopic approach in a specialised centre encompassing specialist pituitary surgeons working in...