Endocrine Abstracts

Background: X-linked Adrenoleukodystrophy, is a rare genetic neurodegenerative disease with an overall incidence of 1:20,000 males1. The disease is characterised by progressive demyelination in the central and peripheral nervous system and adrenal insufficiency as a consequence of the accumulation of very long chain fatty acids [VLCFA] in the myelin of the central nervous system and the adrenal cortex. There is no known genotypic-phenotypic correlation, and the degr...

Cardiac complications including cardiac arrest in Diabetic Ketoacidosis (DKA) have been reported in adults but is not common in children. We present a case of a 3½ year old child with new onset Type 1 Diabetes who presented in severe DKA and went into cardiac arrest needing prolonged resuscitation after starting insulin infusion due to rapid drop of serum potassium (K+). Serum K+ on presentation was 2.8 mmol/l and dropped to 1.5 mmol/l within 2.5 h of starting insulin lea...