ea0026p364 | Adrenal medulla | ECE2011
Lendvai N L
, Szabo I S
, Toth M T
, Forizs E F
, Solyom E S
, Beko G B
, Igaz P I
, Racz K R
, Patocs A P
Background: Pheochromocytomas (Pheo) and paragangliomas (PGL) are rare, mostly benign tumors. Most of these tumors are sporadic but a significant percentage can be found as components of hereditary tumor syndromes caused by germline mutations of the VHL, RET, NF1, SDHD, SDHC, SDHB and the recently identified SDHAF2 genes. Germline mutations of these genes can be also found in several cases with apparently sporadic Pheo/PGL.<...