Searchable abstracts of presentations at key conferences in endocrinology

ea0014p285 | (1) | ECE2007

Frequency of three major glucocorticoid receptor gene polymorphisms in patients with adrenal incidentalomas

Antic Jadranka , Cokic Bojana Beleslin , Ognjanovic Sanja , Vignjevic Jovana , Mirkovic Katarina , Nikolic Jelena , Paunovic Ivan , Damjanovic Svetozar

Background: Several polymorphisms of glucocorticoid receptor (GR) gene, including BclI, N363S and ER22/23EK, which may have an influence on glucocorticoid sensitivity, have been reported. BclI and N363S polymorphisms have been associated with clinical characteristics of increased and ER22/23EK of decreased glucocorticoid (GC) effects. On the other hand, metabolic syndrome has been described in patients with adrenal incidentalomas.Objective ...

ea0014oc4.6 | Neuroendocriology basis | ECE2007

Metabolic abnormalities in patients with adrenal adenomas may be associated with BclI polymorphism in the glucocorticoid receptor (GR) gene and expression of tumor-specific hsp70 isoforms

Damjanovic Svetozar , Antic Jadranka , Beleslin Bojana , Ognjanovic Sanja , Vignjevic Jovana , Petakov Milan , Macut Djuro , Paunovic Ivan , Isailovic Tatjana , Popovic Bojana , Bozic Ivana

Introduction: Intronic BclI polymorphism of glucocorticoid receptor (GR) gene and adrenal adenomas of incidental discovery are frequently associated with metabolic syndrome. We studied in these patients metabolic and hormonal parameters, the sequence alteration in BclI polymorphism of the GR gene from constitutive DNA and the expression of Hsp70 within the tumor and in tissue adjacently to tumor.Patients and methods: We assessed 114 healthy...

ea0056p91 | Clinical case reports - Pituitary/Adrenal | ECE2018

Intracerebral hemorrhage as a first sign of pheochromocytoma

Djurdjevic Sandra Pekic , Jovanovic Vladimir , Tasic Goran , Paunovic Ivan , Tatic Svetislav , Dundjerovic Dusko , Doknic Mirjana , Miljic Dragana , Stojanovic Marko , Jemuovic Zvezdana , Djurovic Marina Nikolic , Popovic Vera , Petakov Milan

Pheochromocytomas and sympathetic paragangliomas are rare catecholamine-secreting tumors and represent very rare causes of intracerebral hemorrhage in young. Few cases of these neuroendocrine tumors which presented with intracerebral hemorrhage have been reported. A 32-year-old man presented to our emergency department because of sudden onset of severe headache. He has a six months history of headache, palpitations and sweating. During examination he became somnolent and devel...