ea0007p24 | Cytokines and growth factors | BES2004
Wong S
, Cresswell P
, English P
, Wilding J
, Huda M
, Pazmany L
, Pinkney J
, Hart I
The multisystem disorder POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) is a rare plasma cell dyscrasia. Elevated cytokines may contribute to its pathogenesis. We describe a POEMS patient with elevated plasma cytokines and excessive daytime sleepiness (EDS).A 39-year-old white woman with IgA lambda and IgG kappa paraproteinaemia, peripheral axonal sensorimotor neuropathy, moderate anascara, skin thickening a...