Endocrine Abstracts

Type 1 diabetes (T1D) is part of a group of disorders termed ‘organ-specific autoimmune diseases’, involving destructive inflammation focused on the insulin-producing beta cells in the islet of Langerhans. Patients (frequently children) lose endogenous insulin production and are required to inject insulin several times per day for the remainder of their lives, and, after many years, frequently develop severe life-threatening complications affecting the kidneys, heart...

Background and aims: European action for the Diagnosis of Early Non-clinical Type 1 diabetes For disease Interception (EDENT1FI) targets early Type 1 Diabetes (T1D) detection to reduce the risk of diabetic ketoacidosis, delay disease progression, improve long-term health outcomes and provide a ‘softer landing’ to insulin therapy. It aims to refine screening and support in early-diagnosed individuals to allow implementation in the clinical care setting.<p class="a...