Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep865 | Thyroid cancer | ECE2015

Incidental papillary thyroid carcinoma prevalence in benign multinodular goitre: data from Northern Portugal

Pereira Maria Teresa , de Carvalho Andre Couto , Freitas Claudia , Borges Fatima

Introduction: Incidental papillary thyroid carcinoma (PTC) in patients undergoing thyroidectomy for benign multinodular disease is a well-recognised finding. Its true prevalence remains uncertain and shows great variability between studies, ranging from 7–25%. Our purpose was to review the prevalence of PTC in thyroid glands removed for benign nodular disease at a Northern Portuguese tertiary hospital.Methods: From December 2012 to December 2014, th...

ea0090ep323 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Programmed cell death-1 inhibitor-induced Type 1 Diabetes Mellitus – an interesting case presenting with diabetic ketoacidosis

Maia Ariana , Rodrigues Catarina Cidade , Soares Daniela , Monteiro Silvia Santos , Pereira Maria Teresa , Amaral Claudia , Cardoso Maria Helena

Introduction: Immunotherapy has demonstrated a key role in the current individualized treatment of multiple neoplasms, with adverse events related to the endocrine. Thyroid dysfunction is the most frequent reported endocrine event during treatment with pembrolizumab, being autoimmune diabetes an extremely rare adverse effect.Case Report: We present a case of a 72-year-old man with a progressing urothelial bladder carcinoma (stage IIIB), under treatment w...

ea0037ep460 | Diabetes (complications & therapy) | ECE2015

Establishing the relationship between third-trimester foetal abdominal circumference, birthweight, and neonatal morbidity in gestational diabetes

Pereira Maria Teresa , Garrido Susana , Almeida Raquel , Vilaverde Joana , Pichel Fernando , Pinto Clara , Goncalves Joaquim , Dores Jorge

Introduction: Gestational diabetes (GD) is associated with a significantly higher risk of perinatal complications. It has been suggested that third-trimester (3thT) foetal abdominal circumference (fAC) determination is an important predictor of macrossomia and large for gestational age (LGA).Aims: The purpose of this study was to evaluate the association between the 3thT fAC percentile with birthweight (BW) and adverse neonatal outc...

ea0056ep15 | Adrenal and Neuroendocrine Tumours | ECE2018

IGF-2-oma: a diagnosis to be considered in a patient with a leiomyosarcoma and recurrent hypoglycemia

Fonseca Liliana , Ferreira Lia , Pereira Teresa Alves , Lopes Ana , Almeida Raquel , Vilaverde Joana , Pereira Maria Teresa , Cardoso Helena

Introduction: Non-islet cell tumor induced hypoglycemia (NICTH) is a paraneoplastic phenomenon involving many types of tumors. It is associated with the secretion of incompletely processed precursors of IGF-2 resulting in a persistent insulin-like activity and hypoglycemia. Most commonly, IGF-2–linked hypoglycemia has been observed in patients with solid mesenchymal or epithelial tumors. Typically, elevated IGF-2 levels are associated with suppressed plasma levels of insu...

ea0073pep5.3 | Presented ePosters 5: Thyroid | ECE2021

Is the thyroid nodule location associated with the risk of malignancy?

Vânia Benido Silva , Pereira Maria Teresa , André Carvalho , Cláudia Freitas , Maria Helena Cardoso

IntroductionRecent published studies suggest that the anatomical location of the thyroid nodule may be associated with different risks of malignancy. However, the results are still sparce and little consensual.AimTo evaluate the frequency of nodules on different locations of the thyroid gland and to determine whether their location correlates with different malignancy risks.Methods<...

ea0037ep311 | Calcium and Vitamin D metabolism | ECE2015

Primary hyperparathyroidism presented as humeral brown tumor and multiple bone fractures

Ferreira Lia , Gomes Pedro , Cardoso Pedro , Valente Vitor , Amado Ana , Pereira Maria Teresa , Garrido Susana , Almeida Raquel , Freitas Claudia , Amaral Claudia , Palma Isabel , Borges Fatima

Primary hyperparathyroidism (PHPT) is frequently diagnosed as an incidental finding of hypercalcemia. Overt bone disease (osteitis fibrosa cystica or brown tumor), with history of pathologic fractures is a rare presentation.A 48-year-old woman was admitted in with pain in the right thigh after a trivial fall. She also complained of generalized weakness and lethargy over the last 2 years. Her medical history mention multiple bone fractures in the last 6 y...

ea0035p1134 | Thyroid Cancer | ECE2014

Papillary thyroid microcarcinoma: focus on prevalence, characterization and follow-up during a 10 years time period

Pereira Maria Teresa , Carvalho Andre , Garrido Susana , Caldas Ana Rita , Freitas Claudia , Teixeira Sofia , Valente Vitor , Canha Antonio , Costa Moreira , Bateira Paulo , Borges Fatima

Introduction: Recent studies point to an ever increasing papillary thyroid microcarcinoma (PTMC) prevalence, with a percentage range between 20 and 43% of all differentiated thyroid carcinomas. It is many times considered an ‘incidental’ finding and its clinical behaviour is uncertain.Aims: To characterize a cohort of patients with PTMC, with reference to clinical and pathological variables and outcome.Methods: Data from ...

ea0073aep398 | Endocrine-Related Cancer | ECE2021

Clinical presentation, phenotype, and germline variants of pheochromocytoma and paraganglioma: A three-decade clinical experience

Duarte Diana Borges , Saraiva Miguel , Ferreira Marta Almeida , Ferreira Lia , Pereira Maria Teresa , André Carvalho , Cláudia Amaral , Vilaverde Joana , Cláudia Freitas , Dores Jorge , Carvalho Rui , Palma Isabel

IntroductionPheochromocytomas are rare catecholamine-producing neuroendocrine tumours arising from chromaffin cells of the adrenal medulla or extra-adrenal sympathetic paraganglia(paragangliomas).AimTo characterise demographic, clinical, and biochemical/genetic features of a cohort of patients with pheochromocytoma and paraganglioma (PPGL), assessing for differences between two-time periods over a three-decad...