Endocrine Abstracts

Background: Although colonic polyps are associated with states of GH excess, no association with gastric polyps has been reported. We describe 2 patients who were treated with rhGH for non-GH deficient growth disorders and who were subsequently found to have gastric polyps.Patient 1: A girl aged 13.6 year with short stature was found to have Turner’s syndrome in the course of being investigated for abdominal pain, diarrhoea and rectal bleeding. Endo...

Biochemical assessment of control of CAH includes measurement of adrenal-derived androgens in blood. Some androgens like 17-hydroxyprogesterone (17OHP) have a diurnal rhythm and show a widespread of values in well controlled children. Testosterone in children (except pubertal boys) may be useful in monitoring control as it may reflect the potential for androgen action better than weaker androgens. Our salivary testosterone (SalT) assay measures free testosterone and is sensiti...

Introduction: Thyroid imaging in the newborns referred with TSH elevation is helpful in establishing a lifelong diagnosis of congenital hypothyroidism (CH), in defining the cause and hence assisting with genetic counselling and in gauging thyroxine requirement.Study aims: To compare diagnostic success when using one, two, three or all four (Quattro mode) of the following modalities – pre-treatment venous thyroid function tests (TFTs), quantitative t...