Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp4 | Adrenal | ECE2016

The role of immunochemistry in the SDHx mutations in pheochromocytomas and paragangliomas

Angelousi Anna , Georgios Kyriakopoulos , Pavlos Constantinou , Georgios Zografos , Georgios Piaditis , Theodosia Xoreutaki , Dimitra Rontogianni , Gregory Kaltsas

Introduction: Early detection of succinate dehydrogenase complex (SDH) mutations in patients with pheochromocytoma and paragaglioma (PPC/PGL) has important implications as it is associated with increased risk for malignancy. The use of negative immunohistochemical (IHC) staining for SDH subunit B, D, A (SDHB/-D/-A) has been proposed as an indicator of SDHs mutation and as an effective substitute for the high-cost genetic screening of all of these genes.M...

ea0016p39 | Adrenal | ECE2008

Impaired endothelial morphology and function in patients with subclinical Cushing's syndrome due to single adrenocortical adenomas

Androulakis Ioannis , Kollias Georgios , Markou Athina , Gouli Aggeliki , Anagnostou Tilemachos , Stamatelopoulos Kimon , Papamichael Christos , Piaditis Georgios , Kaltsas Gregory

Background: Subclinical CushingÂ’s syndrome (SCS) due to incidentally discovered adrenal adenomas (AI) has been associated with increased prevalence of hypertension, obesity, and impaired glucose tolerance which are established risk factors for cardiovascular morbidity. Although functional and morphological (structural) changes of endothelium have been correlated with cardiovascular morbidity this has not been looked into detail in patients with adrenal incidentalomas....

ea0016oc5.7 | Reproduction | ECE2008

Hepatic steatosis is not a feature of young lean women with polycystic ovarian syndrome

Markou Athina , Androulakis Ioannis , Mourmouris Christos , Tsikkini Aggeliki , Samara Christina , Alexandraki Krystallenia , Papadavid E , Syriou V , Naka Katerina , Piaditis Georgios , Kaltsas Gregory

Background: Non-alcoholic fatty liver disease (NAFLD) is a very common liver disorder associated with insulin resistance and the metabolic syndrome. Insulin resistance is also a prominent feature even in lean women with the polycystic ovarian syndrome (PCOS). The objective of this study was to identify the presence of NAFLD in young lean women with PCOS.Methods: Fifteen women with PCOS and 10 controls participated in the study.Mean...