Searchable abstracts of presentations at key conferences in endocrinology

ea0019p372 | Thyroid | SFEBES2009

Confirmation of the chromosome 2q37 region as a susceptibility locus for Graves’ disease

Newby P , Pickles O , Franklyn J , Gough S , Simmonds M

Genome wide association (GWA) studies have revolutionised the search for new susceptibility loci for complex diseases such as GravesÂ’ disease (GD), by confirming association of known genes and identifying several novel susceptibility loci. The high density lipoprotein binding protein (HDLBP) on chromosome 2q37 is one such novel locus recently identified by the WTCCC as part of a 14 500 nonsynonymous single nucleotide polymorphisms (SNP) screen performed in 900 UK C...