Endocrine Abstracts

Background: The Freestyle Flash glucose monitoring (Flash GM) is a new technology suitable for children and adolescents with Type 1 Diabetes Mellitus (T1DM). Clinical accuracy, safety and user acceptability of the Flash GM has been demonstrated in a recent study. In 2017 the UK Association of children’s diabetes clinicians (ACDC) launched national guidelines for training healthcare professionals in delivering Flash GM to children with T1DM.Objective...

Background: Animal studies have demonstrated relationships between Vitamin D and glucose homeostasis. There is paucity of evidence examining the relationship between the glycemic control in children with Type 1 Diabetes Mellitus (T1DM) and vitamin D status.Objective: To determine the effects of vitamin D status on the glycemic control in children and adolescents with T1DM.Methods: Retrospective data were collected on 348 children a...

Background: Animal studies have demonstrated relationship between Vitamin D and glucose homeostasis. There is paucity of evidence examining the relationship between the glycemic control in children with type 1 diabetes mellitus (T1DM) and vitamin D status.Objective: To determine the effects of vitamin D status on the glycemic control in children and adolescents with T1DM.Methods: Retrospective data were collected on 348 children an...

Background: Hypocortisolaemia is common in neonates1 and infants following cardiac surgery.2 In critically ill children with other pathologies, hypocortisolaemia may result from accelerated cortisol metabolism and reduced protein binding. However, the timing and frequency of normalisation of cortisol concentrations following infantile critical illness is poorly described.Objective: To describe the natural history of hypocortisolaemi...

Objectives: Diazoxide is first line treatment for hypoglycaemia due to hyperinsulinaemic hypoglycaemia (HH). Although sporadic cases of pulmonary hypertension (PH) have been reported, no HH cohort has been systematically characterised to understand severity and risk factors for diazoxide-induced PH.Methods: To investigate the onset, progress and associated factors in PH, patients with HH who developed diazoxide-induced PH in 4 regional centres were retro...

Background: Transition from paediatric to adult diabetes services is a critical period influencing health outcomes. Ensuring a smooth transition process has been a significant challenge, often associated with a high rates of disengagement and DKA admissions, and clinic non-attendance once the young person is transferred to adult services.Objectives: This study aims to evaluate impact of transition readiness interventions as part of the NHS England Transi...