Endocrine Abstracts

Introduction: The role of vitamin D in GD is poorly understood. The aim was to compare vitamin D levels in newly diagnosed patients with GD with the general population and to correlate vitamin D levels at diagnosis with laboratory and clinical parameters in GD. Moreover, we examined genetic variation in genes involved in the vitamin D metabolism and their association with GD.Material and methods: Levels of vitamin D were compared in 292 patients with new...

Background: The prescription of triiodothyronine (T3) for hypothyroidism is increasing worldwide, however, long-term effects of its use are largely unknown. Previous studies have suggested possible association between T3 use and breast cancer. The aim of the study was to examine the effects of T3 use on cancer incidence and mortality.Material: Our sample included the full adult population of individuals living in Sweden with at least three purchases of t...

Objective: Patients with low thyroid peroxidase antibodies (anti-TPO) and increased TSH-receptor antibodies (TRAb) at diagnosis of Graves’ disease (GD) have been suggested to have an increased risk to develop Graves’ ophthalmopathy (GO). The aim was to evaluate if GO development can be predicted.Design: Observational study with registration of possible GD and GO risk factors.Methods: Three hundred and ninety nine patients...

Introduction: Graves’ disease (GD) can negatively affect the quality of life. Research on GD in childhood, accounting for 1-5% of cases, has so far predominantly focused on treatment results. There is limited knowledge about association with other diseases and long-term psychosocial effects.Aims: We aimed to compare disease burden and psychosocial outcomes between childhood/young adult GD patients and unexposed population controls.<p class="abst...