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ea0077op2.2 | Adrenal and Cardiovascular | SFEBES2021

Single-centre analysis of 900 short synacthen tests: do pre-test clinical or biochemical variables predict failure?

Dilrukshi M D S A , Beck K J , Loo H , May C , Jafar-Mohammadi B , Pofi R , Tomlinson J W , Pal A

Short synacthen test (SST) is the most widely used dynamic test of hypothalamic-pituitary-adrenal (HPA) axis function. Its simple to conduct but requires nursing time and is relatively costly given 15-fold price increase in synacthen since 2015. We audited our SST use with the aim of reviewing clinical indications for testing and identifying useful predictors of test outcome. Baseline referral, clinical and biochemical data were retrospectively collected for individuals ...

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ea0083cbo3 | Calcium and Bone | EYES2022

Bone metabolism and dual-release Hydrocortisone: results from a real-life study

D Ferrari , V Sada , V Hasenmajer , D De Alcubierre , G. Puliani , M Minnetti , A Cozzolino , A Tomaselli , R Pofi , A Lenzi , A Isidori

Background: Patients with adrenal insufficiency (AI) require long-term glucocorticoid (GC) replacement therapy and generally show an increased prevalence of bone metabolism alterations. Only few data are available on bone safety of dual-release Hydrocortisone (DR-HC) therapy. Objective: To evaluate bone metabolism in primary AI (PAI) and secondary AI (SAI) during long-term therapy with DR-HC.Methods: We evaluated patients with AI o...

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Endocrine Abstracts

Single-centre analysis of 900 short synacthen tests: do pre-test clinical or biochemical variables predict failure?

Bone metabolism and dual-release Hydrocortisone: results from a real-life study

BiosciAbstracts