Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep294 | Calcium & Vitamin D metabolism | ECE2017

Severe hypocalcemia induced by Denosumab in a patient with Osteroporosis after malabsorptive bariatric surgery

Portilla Ana Jimenez , Soler Guillermo Serra , Planella Juan Ramon Urgeles , Perez Maria Soledad Gogorza , Font Mercedes Noval , Fernandez Honorato Garcia , Jimenez Inaki Arguelles , Macazaga Vicente Pereg

Introduction: Denosumab is a monoclonal antibody indicated in the treatment of postmenopausal osteoporosis. Hypocalcemia is a rare adverse effect.Case report: We present the case of a 58-year-old woman with a clinical history of bariatric surgery in 2001 and osteoporosis with multiple vertebral and hip fractures. Under treatment with Zinc sulphate, Vitamin A, 25-OH-vitamin D, calcium and iron. She came to the A&E for general malaise, generalized weak...

ea0056p973 | Male Reproduction | ECE2018

Male hypogonadism due to 46, XX Testicular disorder of sex development

Font Mercedes Noval , Soler Guillermo Serra , Portilla Ana Jimenez , Barcelo Carlos Antich , Povedano Santiago Tofe , Ribas Elena Mena , Macazaga Vicente Pereg

Introduction: 46,XX testicular disorder of sex development (DSD) is a rare syndrome, which is characterized by a female karyotype in discordance with a male phenotype. It is presented with primary hypogonadism, gynecomastia and infertility. About 80–90% of 46,XX testicular DSD cases are positive for SRY gene. Appearance of external genitalia and masculinization are usually normal in 46,XX SRY-positive casesClinical case: A 41-year-old male came with...

ea0056p50 | Adrenal cortex (to include Cushing's) | ECE2018

Is the adrenal vein sampling the gold standard diagnostic test for the subtyping of primary aldosteronism?

Portilla Ana Jimenez , Ribas Elena Mena , Bennasar Antonia Barcelo , Ruitort Juan Manuel Martinez , Segurola Cristina Alvarez , Font Mercedes Noval , Barcelo Carlos Antich , Soler Guillermo Serra , Jimenez Inaki Arguelles , Povedano Santiago Tofe , Macazaga Vicente Pereg

Introduction: Primary aldosteronism (PA) is the most common cause of secondary hypertension (5–10%) and it is underdiagnosed. Less than 50% of patients with PA have hypokalemia. The tests for determinate subtype of PA are cross-sectional imaging (adrenal CT or MRI) and adrenal vein sampling (AVS). The AVS seems to be important to direct appropriate therapy and surgery is the preferred treatment for patients with unilateral disease.Material and metho...