Searchable abstracts of presentations at key conferences in endocrinology

ea0050p018 | Adrenal and Steroids | SFEBES2017

Prednisolone should be first line replacement therapy for adrenal insufficiency

Prabhudev Hemanth , Smith David , Choudhury Sirazum , Meeran Karim

Introduction: We offer patients needing glucocorticoid replacement in primary and secondary adrenal insufficiency the choice of either once daily prednisolone or thrice daily hydrocortisone. A recent European study found no difference between prednisolone and hydrocortisone users in several markers, including glucose, weight, body mass index (BMI), systolic and diastolic blood pressure and waist circumference, although they did suggest an increase in cholesterol and low densit...

ea0050p018 | Adrenal and Steroids | SFEBES2017

Prednisolone should be first line replacement therapy for adrenal insufficiency

Prabhudev Hemanth , Smith David , Choudhury Sirazum , Meeran Karim

Introduction: We offer patients needing glucocorticoid replacement in primary and secondary adrenal insufficiency the choice of either once daily prednisolone or thrice daily hydrocortisone. A recent European study found no difference between prednisolone and hydrocortisone users in several markers, including glucose, weight, body mass index (BMI), systolic and diastolic blood pressure and waist circumference, although they did suggest an increase in cholesterol and low densit...

ea0059p058 | Clinical biochemistry | SFEBES2018

A cross-sectional study of sensitivity and specificity of late-night salivary cortisol in a single-centre heterogenous population

Barker Sally , Prabhudev Hemanth , Martin Nimah , Todd Jeannie , Meeran Karim , Agha-Jaffar Rochan , Wernig Florian

Endogenous CushingÂ’s syndrome poses considerable diagnostic challenges. It is recommended to use two screening tests to confirm hypercortisolaemia. While late-night salivary cortisol assessment (LNSC) is reported to have good specificity and sensitivity and deemed to be cost-effective, it is the least widely biochemical tool used both nationally and in Europe. We aim to compare the specificity and sensitivity of LNSC against and in combination with other diagnostic tests,...