Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp29 | Adrenal (2) | ECE2016

Plasma metabolomics profile in patients with Cushing’s syndrome

Dalmazi Guido Di , Quinkler Marcus , Deutschbein Timo , Prehn Cornelia , Rayes Nada , Kroiss Matthias , Fassnacht Martin , Berr Christina , Stalla Gunter , Adamski Jerzy , Reincke Martin , Beuschlein Felix

Background: CushingÂ’s syndrome (CS) is a chronic disorder characterized by endogenous cortisol excess resulting in long-term metabolic and cardiovascular consequences. The identification of metabolic alterations related to hypercortisolism could be beneficial in tailoring treatments of co-morbidities. Our aim was to characterize the metabolic alterations of patients with hypercortisolism by targeted plasma metabolomic profiling.Methods: Subjects (<e...

ea0037gp.05.04 | Developmental and paediatric endocrinology | ECE2015

Pilot study on the effects of cross-sex hormone treatment in transsexual persons on metabolism by means of metabolomics profiling

Auer Matthias K , Xu Tao , Roepke Yasmin , Stalla Gunter K , Stieg Mareike , Van Caenegem Eva , Prehn Cornelia , Wang-Sattler Rui , Adamski Jerzy , T'sjoen Guy

Introduction: Sex steroid hormones exert a wide range of effects on metabolism. New techniques such as metabolomic profiling allow for a deeper insight into metabolic regulation. In epidemiological samples it has been demonstrated that most of these metabolites show sex-specific differences. However, if these differences are attributable to the effects of sex hormones or genetics is little understood so far.Methods: We performed targeted metabolomics pro...