ea0081ep589 | Endocrine-Related Cancer | ECE2022
Rosu Andreea
, Ambăruş - Popovici Ioana
, Chiriac Bianca
, Blesneac Ilona - Beatrice
, Proţop Mădălina
, Patraşcu Ana-Maria
, Scripcariu Viorel
, Preda Cristina
Introduction: Ovarian hyperthecosis (OH) is a rare condition, reported only in case reports and small case series and is characterized by severe hyperandrogenism leading to virilisation and insulin resistance. The term hyperthecosis refers to the presence of luteinized thecal cells within a hyperplastic ovarian stroma and the pathophysiology of this remains poorly understood. Despite the fact that hyperandrogenism is a relatively common clinical problem, severe hyperandrogenis...