Endocrine Abstracts

Chordomas of the skull base are rare lesions, which account for less than 0.2% of all intracranial tumours. They arise from embryonic remnants of the primitive notochord. They are described as locally aggressive, rarely metastatic tumours with a tendency to frequent relapses. They usually grow slowly with the destruction of the surrounding tissues. The symptoms are very unspecific which is the cause of the delay of the diagnosis. The most common initial symptoms are headaches ...