Searchable abstracts of presentations at key conferences in endocrinology

ea0020p87 | Thyroid | ECE2009

Long-term exogenous subclinical hyperthyroidism is not associated with decrased bone mineral density in men with differentiated thyroid carcinoma

Colome Eulalia , Reverter Jordi L , Holgado Susana , Puig Rocio , Alonso Nuria , Sanmarti Anna

Objectives: To determine the effect on bone mineral density (BMD) of the sub clinical hyperthyroidism (SH) due to TSH-suppressive treatment with levothyroxine after thyroidectomy in men with differentiated thyroid carcinoma (DTC).Materials and methods: Cross-sectional and retrospective study in 32 men (56±14 years) treated with levothyroxine for a minimum of 5 years, with TSH concentrations <0.05 mUI/ml and normal T3 levels in all determinations...

ea0056gp155 | Obesity | ECE2018

Changes in gut microbiota and metabolic profiles after sleeve gastrectomy

Puig Rocio , Pellitero Silvia , Martinez Eva , Tarasco Jordi , Moreno Pau , Vilarrasa Nuria , Vendrell Joan , Fernandez Sonia , Puig-Domingo Manel

We aimed to assess the effect of sleeve gastrectomy (SG) on the metabolic and gut microbiota profiles in non-diabetic obese patients with different grade of insulin resistance (IR).Methods: Prospective study of 22 morbid non-diabetic obese patients (77.2% women, age 47.13±9.51 years, basal BMI 45.59±4.99 kg/m2, 11 IR and 11 non-IR) undergoing SG. A fasting blood sample was collected at baseline and at 6 months post-SG for the determi...

ea0081ep318 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Role of incretins, gut microbiota and permeability in the remission of type 2 diabetes mellitus after bariatric surgery

Hernandez-Montoliu Laura , Puig Rocio , Pellitero Silvia , Vendrell Joan , Fernandez-Veledo Sonia , Guerrero Fernando , Vidal Anna , Rodriguez M. Mar , Montseny Rosa , Vilarrasa Nuria

Introduction: Bariatric surgery is an effective therapy for patients with type 2 diabetes mellitus (T2D). Many mechanisms have been proposed for its metabolic benefits, such as caloric restriction, weight loss, increased secretion of gut hormones like glucagon-like peptide 1 (GLP-1) and 2 (GLP-2), bile acid diversion, decrease of pancreatic and hepatic fat deposits and changes in gut microbiome.Aims: Evaluate changes after surgery in gut microbiome profi...

ea0016p140 | Clinical cases | ECE2008

Prospective study of latent pernicious anemia markers in patients with type 1 diabetes mellitus

Alonso Nuria , Granada MaLuisa , Soldevila Berta , Salinas Isabel , Aguilera Eva , Junca Jordi , Puig Rocio , Pla Raquel , Martinez-Caceres Eva , Sanmarti Anna

Introduction: Patients with type 1 diabetes mellitus (DM1) present a high prevalence of autoimmune associated diseases. Recently, we described a prevalence of latent pernicious anemia (LPA) of 12.4% in DM1.Objectives: A 5-year follow-up study of a cohort of DM1 patients in order to evaluate the evolution of biochemical markers of LPA, defined as a serum pepsinogen I (PI) concentration below normal limits.Material and methods: One h...

ea0056gp116 | Diabetes Translational | ECE2018

The role of oncostatin m in the development of type 2 diabetes associated with obesity

Taxeras Siri , Piquer-Garcia Irene , Pellitero Silvia , Puig Rocio , Martinez Eva , Tarasco Jordi , Moreno Pau , Bombuy Ernest , Higueras Carmen , Malagon Paloma , Lerin Carles , Puig-Domingo Manel , Sanchez-Infantes David

Background: Obesity can lead type 2 diabetes (T2D), however there are patients with obesity who present euglycemia. The mechanisms by which T2D appears have not been fully elucidated. Oncostatin m (OSM) is a proinflammatory cytokine, member of the IL-6 family, which is increased in obesity in mice and humans, and impairs browning in mice. Here, we aim at evaluating the potential role of OSM in the development of T2D in patients with obesity.Material and ...