Searchable abstracts of presentations at key conferences in endocrinology

ea0020p141 | Thyroid | ECE2009

Thyrotropin suppression by metformin in a cohort of patients with differentiated thyroid cancer in follow-up

Citarrella Roberto , Puleo Luciana , Chiofalo Francesco , Smeraldi Lucia , Nucera Miriam , Richiusa Pierina

Background: It has been reported that metformin might modify thyroid hormone economy. This farmacological tool appears very useful in patients with differentiated thyroid cancer usually receiving high Levo-tiroxine (L-T4) doses to suppress thyrotropin (TSH). In those patients that after five years of follow-up showed no persistence of disease, itÂ’s useful to abolish the iatrogenic hyperthyroid condition.Objective: To evaluate metformi...

ea0020p449 | Obesity and Metabolism | ECE2009

Metabolic syndrome highly correlates to non toxic multinodular goiter progression: iperinsulinism a way to growth

Citarrella Roberto , Chiofalo Francesco , Vetro Calogero , Lo Coco Alessio , Puleo Luciana

Background: Insulin-resistance phenomenon is a key factor in the pathogenesis of Metabolic Syndrome (MS). Several reports focus on the identification of a role of Insulin to trigger thyrocytes proliferation in vitro. Thyroid IRS-1 mRNA expression increased progressively during goitrogenesis in vivo. In order to individuate the impact of clinical and biochemical markers of MS on the growth-score of non toxic multinodular goiter (MNG) we evaluated a population of 6...

ea0084ps1-03-21 | Thyroid Cancer CLINICAL 1 | ETA2022

Risk of structural recurrence in differentiated thyroid carcinoma (DTC) patients without evidence of disease after initial treatment: insights into risk factors and comparison with american thyroid association guidelines

Contartese Lea , Gambale Carla , Prete Alessandro , Puleo Luciana , Cappagli Virginia , Lorusso Loredana , Agate Laura , Molinaro Eleonora , Elisei Rossella , Matrone Antonio

Background: The last American Thyroid Association guidelines (ATA-2015) defined the risk of structural recurrence in patients with DTC cured after initial treatment and according to the initial histology. However, these data resulted from several studies including different patients with different kinds of treatment. We retrospectively evaluated a large population of patients with DTC, treated and followed in a tertiary referral center, with the aim to characterize the rate of...