Endocrine Abstracts

Objective: Sperm cells are produced in the testes by the Sertoli cells. These cells produce Inhibin B and they are stimulated by FSH. Can Inhibin B be a good marker of spermatogenesis? Should we use other marker (FSH?, testosterone?)Design: Prospective study.Patients: We examined 71 patients with infertility.Methods: Semen analysis and hormonal analysis was performed. Semen analysis was performed according to...

Analogues of somatostatin are widely used in management of neuroendocrine tumors. The “classic” indications for this treatment are: acromegaly and NETs of midgut to diminish symptoms caused by hormonal overproduction and slow down the tumors’ growth. However we consider the use of this medication also in the other cases in which we confirm the presence of somatostatin receptors in tumor by somatostatin receptor scintigraphy.We would like t...

In secondary adrenal insufficiency (SAI), the Synacthen test can give a false negative result. If disease is strongly suspected, an insulin hypoglycaemia test or Metyrapone (Metopirone) test should be carried out. Insulin test could be hazardous for patients with adrenal insufficiency (due to high risk of severe hypoglycaemia), so in our clinic we use overnight single-dose Metyrapone test. Although this test is easy to perform, measurement of 11-deoxycortisol concentration is ...