Endocrine Abstracts

Bacground: It is disputable whether negative effects of comorbid depression in patients with type 2 diabetes can be diminished by treatment of depression. The primary aim of this study was to assess whether addition of antidepressants to existing insulin therapy would further improve glycemic control in these patients. A secondary objective was to assess whether such treatment impairs their lipid and inflammatory status.Material/methods: Total of 50 pati...

Background and aims: Plasminogen activator inhibitor -1 (PAI-1) increases in diabetes and this might contribute to decreased fibrinolisis and accelerated atherosclerosis. PAI-1 is also contributor to the development of acute myocardial infarction. Measurement of intimal medial thickening (IMT) is indicator of presence and extent of coronary artery disease. Aim of the study was to find association between PAI-1 marker of decreased fibrinolisis and atherosclerosis by measuring I...