Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep806 | Reproductive and Developmental Endocrinology | ECE2020

Seasonal changes of serum gonadotropins and testosterone in men revealed by a large data set of real-world observations over nine years

Spaggiari Giorgia , Raffaele Michele Granata Antonio , Setti Monica , Tagliavini Simonetta , Trenti Tommaso , Simoni Manuela , Santi Daniele

Background: Environmental rhythmicity seems able to affect the hypothalamic-pituitary-gonadal axis in animals to achieve reproductive advantages. However, conflicting results were obtained when assessing the environmental-dependent rhythmicity on reproductive hormone secretion in humans.Aim of the study: This study was designed to evaluate seasonal fluctuations of the main hormones involved in the hypothalamic-pituitary-gonadal axis in men, using a big d...

ea0090p82 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Testosterone serum levels predict the severity of metabolic dysfunction associated fatty liver disease (MAFLD) in hypogonadal men

Santi Daniele , Spaggiari Giorgia , Nascimbeni Fabio , Lugari Simonetta , Felicani Cristina , Dalla Valentina Leonardo , Ahmad Ali , Raffaele Michele Granata Antonio , Andreone Pietro , Simoni Manuela

Background: Metabolic dysfunction associated fatty liver disease (MAFLD), the leading cause of chronic liver disease, is defined as the presence of hepatic steatosis and metabolic risk factors. Both testosterone and estradiol seem to have a pivotal role in hepatic lipid homeostasis, although underlying mechanisms are still unclear. Low testosterone serum levels result independently associated with MAFLD, but no studies so far evaluated MAFLD prevalence and severity in hypogona...