Endocrine Abstracts

Case history: 58 year old man presented with collapse secondary to profuse water diarrhoea. He had severe AKI, hypokalaemia, metabolic acidosis, hyponatraemia and hypercalcaemia. He had fluid and electrolyte replacement he in ICU, but profuse diarrhoea persisted and with it, was in hypotension and delerium. He had been having progressive diarrhoea and weight loss for 2 years while he was in South Africa.Investigations: Upper and lower GI endoscopies had ...

68 year old lady was on amiodarone for atrial fibrillation and poor left ventricular systolic function. She was feeling unwell, so she had some blood tests which showed elevated free T4 and suppressed TSH. She did not have a family history of thyroid disease. She did not have a goitre or eye signs. She did not have overt signs of thyrotoxicosis. She was admitted as her heart failure was not controlled and her diuretics were optimised. Her thyroid antibodieswere checked and was...

61 year male presented with productive cough and was noted to have persistent hypokalaemia. On examination he had an elevated blood pressure; previously not known to be hypertensive and significant proximal myopathy in his lower limbs. He also had central obesity. In October 2018 he had a left parotid swelling. He had left parotidectomy and left neck dissection. The histology was an adenocarcinoma. In the following year he had cough, and shortness of breath, which on investiga...

Case history: Our patient is a 64 year old lady who had bilateral adrenalectomy in 1978 for Cushing”s disease. This was followed by radiotherapy in late 1978. To get further reduction of the ACTH producing pituitary adenoma she had transsphenoidal surgery in 1979 and then transfrontal craniotomy in 1982. This was followed by further radiotherapy in 1985. It left her with panhypopituitarism and she was on full hormone replacement. She presented to our hospital in late 2008...

Context: NICE and BTA agrees that combination L T4 and LT3 can be used in patients with symptoms persisting after adequate use of LT4.Methods: We retrospectively audited the patients coming to the endocrine clinics of ESHT whether they followed the local agreed protocol of LT3 usage. We checked if they had:1. Initiation of LT4 by an endocrine specialist.2. If other causes of tiredness were ruled out.<p cl...

32 year old female presented to her GP following a first trimester miscarriage which consequently resulted in her experiencing secondary amenorrhoea for more than 9 months. Secondary amenorrhoea is defined as cessation of regular menses for 3-6 months or the cessation of irregular menses for 6-12 months. Her main concern was around her subfertility and dry skin. She started menarche at the age of 10 with regular monthly menses until her copper coil insertion 4 years ago. She h...