Endocrine Abstracts

Introduction: There is a clinical need to develop better biomarkers for the monitoring of patients with neuroendocrine tumours (NETs), including for patients with multiple endocrine neoplasia (MEN). Chromogranins are widely used, as are individual hormones for specific syndromes. Neurone specific enolase (NSE), however, is measured less commonly and its utility is debatable.Aims: To assess the value of measuring NSE in the clinical management of patients...

59 year old woman with relapsing remitting multiple sclerosis (MS), not under Neurology follow-up was privately consulting a nutritionist based in Ireland and following the Coimbra protocol1 since December 2016. This included colecalciferol (1000-170000 IU/ day), vitamin B-complex and trace elements. Dose adjustments were advised during weekly skype consultations based on blood tests (via General Practitioner) and symptoms.<p class="abstex...

59 year old woman with relapsing remitting multiple sclerosis (MS), not under Neurology follow-up was privately consulting a nutritionist based in Ireland and following the Coimbra protocol1 since December 2016. This included colecalciferol (1000-170000 IU/ day), vitamin B-complex and trace elements. Dose adjustments were advised during weekly skype consultations based on blood tests (via General Practitioner) and symptoms.<p class="abstex...

Background: The main dilemma in hyponatraemia management is that of fluid restriction vs fluid administration. Inappropriate fluid management may result in either cerebral oedema/death or permanent neurologic disability due to rapid sodium correction. Objective: We explore the utility of point of care ultrasound (POCUS) as an adjunct tool for assessing 3-volume groups (Hypovolaemia, Euvolaemia & Hypervolaemia) in severe hyponatraemia (Na<120 mmol...

Background: One of the main indications for parathyroidectomy surgery in primary hyperparathyroidism (PHPT) is osteoporosis. NICE guideline recommends 2-3 yearly Dual-energy X-ray absorptiometry (DEXA) assessments to evaluate bone mineral density (BMD) in asymptomatic PHPT. Objective: We undertook an audit to evaluate bone health practice in PHPT patients in line with NICE guidelines.Methodology: Retrospective case notes and electr...

Background: Conventional treatment for chronic hypoparathyroidism (CHP) is Vitamin-D analogues and calcium supplementation, not replacement of lacking hormone, as done in other hormone-deficiency states.Objectives: Retrospective evaluation of CHP management in line with European Society of Endocrinology Guideline was undertaken, to assess adequacy of calcium-homeostasis and morbidity.Methodology: Retrospective case-note and electro...