Searchable abstracts of presentations at key conferences in endocrinology

ea0059p139 | Neuroendocrinology and pituitary | SFEBES2018

Postoperative metabolic profile of patients after pituitary surgery

Rajaratnam Simon , Jeyaseelan Lakshmanan , Chacko Ari George

Objective: To study the metabolic profile of patients after surgery for pituitary tumors.Methods: This retrospective study included 1138 patients from 2000 to 2017. Those with prolactinomas, pituitary apoplexy and surgery elsewhere were excluded. The analysis included 525 patients, non-functional tumors (143), acromegaly (267), Cushing’s disease (113) and TSHoma (1). The patients’ blood pressure, blood sugar, lipid profile and body mass index (...

ea0015p131 | Diabetes, metabolism and cardiovascular | SFEBES2008

Factors effecting CHD risk reduction in patients with type 2 diabetes and microalbuminuria

Rajaratnam Simon , Phillipov George , Phillips Patrick

The UKPDS study has shown that, intensive lowering of blood sugar and blood pressure decreases the risk of micro vascular complications in individuals with type 2 diabetes. The Steno-2 study has shown that target driven, long-term intensive treatment in patients with type 2 diabetes and microalbuminuria reduces the risk of cardiovascular and micro vascular events by about 50%.We investigated the effect on the 10 years absolute CHD risk of our type 2 diab...

ea0031p339 | Steroids | SFEBES2013

Spot urine cortisol: creatinine ratio: a useful screening test for patients with Cushing's syndrome

Paul Thomas , Kapoor Nitin , Job Victoria , Lakshmanan Jeyaseelan , Rajaratnam Simon

Introduction: Cushing’s syndrome(CS) is associated with high morbidity and mortality which warrants a good screening test that is less laborious. We explored the possibility of using urine spot cortisol:creatinine ratio (UCCR) as a new screening test for Cushing’s syndrome.Aims and objectives: To study the efficacy of UCCR as a screening test for patients with Cushing’s syndrome.To compare UCCR in patients with CS, o...

ea0031p27 | Bone | SFEBES2013

The diagnosis of osteoporosis among subjects of Southern Indian origin above 50 years of age: the impact of the indian council of medical research vs caucasian bone mineral density reference standards

Paul Thomas , Mruthyunjaya Mahesh , Shyamasunder Asha , Naik Dukhabandu , Rajaratnam Simon , Thomas Nihal , Seshadri Mandalam

Introduction: In the year 2010, the Indian Council of Medical Research (ICMR) has published a normative data for mone mineral density (BMD) measured by dual energy X-ray absorptiometry (DXA) scanning. However, its impact on the diagnosis of osteoporosis when compared to currently used Caucasian database has not been analysed.Objectives: To study the effect of the newly generated ICMR database (ICMRD) on the diagnosis of osteoporosis compared with the Hol...

ea0031p31 | Bone | SFEBES2013

AUDIT of patients referred for DXA scanning in a south Indian Tertiary care centre

Paul Thomas , Mruthyunjaya Mahesh , Shyamasunder Asha , Naik Dukhabandu , Rajaratnam Simon , Thomas Nihal

Introduction: Osteoporosis is a silent disease and fractures pose enormous medical and financial burden on ageing individuals. Also subjects of younger age are at risk for subnormal bone mineral density when they have systemic disorders like rheumatoid arthritis or on long-term medications like corticosteroids. Preventive measures can be initiated if osteoporosis is diagnosed and treated before any fracture occurs. Even after the first fracture has occurred, there are effectiv...

ea0015p101 | Clinical practice/governance and case reports | SFEBES2008

Infectious causes of adrenal insufficiency: a report from South India

Lau Sue Mei , Sarawagi R. , Behera Kishore Kumar , Paul Thomas , Rajaratnam Simon , Thomas Nihal , Seshadri Mandalam Subramaniam

Aim: To determine the aetiology of Addison’s disease in patients admitted to a tertiary care hospital in South India from 2001 to 2007.Method: Forty-five patients with Addison’s disease were admitted during this period. Etiological work up was carried out in all these patients.Results: Thirteen patients (29%) had a possible infectious cause: 11.1% histoplasmosis, 8.8% confirmed tuberculosis, 4.4% presumed tuberculosis, 4...

ea0028p42 | Clinical practice/governance and case reports | SFEBES2012

Endoscopic ultrasonography is a sensitive tool in the preoperative localization of insulinoma

Joseph A , Kapoor Nitin , Asha H , Simon Ebby , Chacko Ashok , Thomas Elsa , Eapen Anu , Ramakrishna Banumathi , Abraham Deepak , Paul M , Paul Thomas , Thomas Nihal , Rajaratnam Simon

Introduction: Various imaging modalities are used in the preoperative localization of insulinoma. CT is the modality that is in widespread use. Endoscopic ultrasound (EUS) allows the transducer to be placed in close proximity to the pancreas, thereby yielding images of higher quality, leading to accurate localization. An accurate preoperative localization results in a minimal invasive surgery and less occurrence of residual tumors, translating into a better clinical outcome. O...

ea0015p208 | Neuroendocrinology and behaviour | SFEBES2008

Craniopharyngioma: a single institutional experience from South India

Sivan Arul Selvan S , Felix Jebasingh K , Rajaratnam Simon , Thomas Paul V , Thomas Nihal , Mandalam Subramaniam Seshadri , Simon Anna , Chacko Ari George , Vedantam Rajshekhar , Thomas Daniel Roy

Introduction: Craniopharyngiomas constitute 2–5% of all primary CNS neoplasms. We retrospectively analysed the case records of all patients with craniopharyngioma treated in our hospital from 1996 to 2006.Results: One hundred and twenty-seven patients were treated during this period. 65% were male and 35% were female. 50 patients (39%) were <15 yrs of age. The maximum clustering of cases was in the 6–15 yr age group (37%).<p class="abs...

ea0038p77 | Clinical practice/governance and case reports | SFEBES2015

Phaeochromocytoma: experience from a single centre in South India

Naik Dukhabandhu , Das Gupta Riddhi , Asha H S , Paul Thomas V , Kapoor Nitin , Mahesh D M , Cherian Anish Jacob , Abraham Deepak T , Shanthly Nylla , Oomen Reji , Chandramohan Anuradha , Ramakrishna Banumathi , Pai Rekha , Paul M J , Rajaratnam Simon , Thomas Nihal

Phaeochromocytoma (PCC) and paragangliomas (PGL) are neuroendocrine tumours derived from the embryonic neural crest, located either within the adrenal gland or at extra-adrenal sites.Objective: To study the clinical, biochemical, imaging characteristics, and mutational profile of patients with PCC/PGL treated at our institution.Methods: We collected data of patients with PCC/PGLs managed at Christian Medical College, Vellore, India...