ea0056oc2.3 | Look who is controlling your gonads! | ECE2018
Krausz Csilla
, Riera-Escamilla Antoni
, Chianese Chiara
, Moreno-Mendoza Daniel
, Rajmil Osvaldo
, Ruiz-Castane Eduard
, Surralles Jordi
Background: The etiology of non-obstructive azoospermia (NOA) remains unknown in about 40% of cases and genetic factors are likely to be involved in a large proportion of them. Gene mutations involved in stem cell proliferation and DNA repair may cause isolated NOA or be responsible for syndromic diseases, such as Fanconi Anemia (FA). Although the most frequent presenting symptom in FA is bone marrow failure in childhood, in about 10% of cases the diagnosis is delayed until ad...