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ea0099p134 | Pituitary and Neuroendocrinology | ECE2024

Macroprolactin over time: Is there any point in rechecking it in people with a persistently elevated serum prolactin?

Heald Adrian , Hashimi Syeda , Warner-Levy John , Ramachadran Sudarshan , Laing Ian , Livingston Mark

Design: Macroprolactinemia may influence the interpretation of serum prolactin levels – a recognised phenomenon since 19781. The degree of macroprolactinaemia over time is less well described. We determined how macroprolactin status (based on polyethylene glycol (PEG) precipitation varied by analysing serial measurements in hyperprolactinaemic individuals over nine years.Patients and Measurements: Results from 1810 individuals were includ...