Searchable abstracts of presentations at key conferences in endocrinology

ea0080OC3 | Oral Communications | UKINETS2021

An update on the effects of debulking surgery and liver directed intra-arterial therapies on quality of life in patients with metastatic neuroendocrine tumours

Woods Eleanor , Sinclair Adam , Jarvis Emma , Ramsey Emma , Tanno Lulu , Naheed Salma , Armstrong Thomas , Takhar Arjun , Knight John , Stedman Brian , Modi Sachin , Bryant Timothy , Breen David , Nolan Luke , Al-Mrayat Ma'en , Pearce Neil , Cave Judith

Background: Neuroendocrine tumours (NETs) arise from neuroendocrine cells, they are commonly found in the pancreas, small bowel and lung. They are a heterogeneous group of tumours capable of secreting a variety of hormones, therefore the spectrum of symptoms is broad. Treatment options for metastatic NETs include cytoreductive surgery, or interventional radiology procedures such as transarterial embolization (TAE). Aims: Previous studies have shown that ...

ea0068p23 | Abstracts | UKINETS2019

Effects of debulking surgery, transarterial embolisation (TAE) and transarterial chemoembolisation (TACE) on quality of life in patients with metastatic ileal and pancreatic neuroendocrine tumours (NETs)

Sinclair Adam , Tanno Lulu , Jarvis Emma , Ramsey Emma , Naheed Salma , Armstrong Thomas , Takhar Arjun , Knight John , Stedman Brian , Modi Sachin , Bryant Timothy , Breen David , Nolan Luke , Al-Mrayat Ma'en , Pearce Neil , Cave Judith

Neuroendocrine tumours (NETs) are a heterogenous group of tumours that arise from neuroendocrine cells throughout the body. Debulking surgery is offered to patients with metastatic NETs and is recommended in the ENETS guidelines. This study was undertaken to evaluate the impact of debulking surgery and liver directed therapy (TACE, TAE) in metastatic NETs, on quality of life (QoL). Prospective longitudinal cohort study was undertaken at University Hospital Southampton. Patient...

ea0046p19 | (1) | UKINETS2016

Patient outcomes after cardiac surgery for carcinoid heart disease are dependant upon successful cytoreductive multimodal treatment and control of metastatic neuroendocrine disease

Jaber Basher , Ramsey Emma , Cowburn Peter , Tsang Geoff , Pearce Neil , Knight John

Introduction: Carcinoid Heart Disease (CHD) can occur in up to 50% of patients with long standing carcinoid syndrome as a result of metastatic neuroendocrine tumour (NET). It is associated with poor prognosis due to the development of right side heart failure. High circulating levels of serotonin cause cardiac fibrosis leading to tricuspid and pulmonary valve regurgitation and poor ventricular function. Cardiac surgery with valve replacement in combination with cytoreductive s...

ea0046p20 | (1) | UKINETS2016

Initial experience of a novel technique for endoscopic full thickness resection of rectal neuroendocrine tumours

Fong Michelle , Ramsey Emma , Boger Philip , Patel Praful , Ellis Richard , Knight John

Introduction: Standard endoscopic resection of rectal neuroendocrine tumours (NETs) is often associated with histological incomplete excision due to the submucosal position of the tumour within the bowel. This can lead to multiple attempts to achieve a complete excision or uncertainty leading to ongoing endoscopic surveillance. Endoscopic full thickness resection may allow early definitive management. We report a simple definitive technique for the full thickness excision of r...

ea0074oc4 | Oral Communications | SFENCC2021

Synchronous functional heterogeneity of metastatic pancreatic neuroendocrine tumour

Sim Sing Yang , Ramsey Emma , Cave Judith , Fityan Adam , Green Bryan , Al-Mrayat Ma'en

A 65 years old male chef presented with a history of weight loss of 15kg over a 12-month period associated with lethargy, constipation and abdominal pain. His past medical history included epilepsy, hypertension and gastric reflux. He reported no family history of endocrinopathies.At presentation his performance status was 0 and was found to have hepatomegaly. In view of rapid weight loss and hepatomegaly he had a CT scan of the abdomen and pelvis, which showed multiple hyperv...