Searchable abstracts of presentations at key conferences in endocrinology

ea0095p95 | Bone 2 | BSPED2023

Unusual presentation of Isolated Hypoparathyroidism in a young adolescent

Ramya Gokul Pon , Blair Jo , Dharmaraj Poonam , Ramakrishnan Renuka

Introduction: Hypoparathyroidism is an uncommon condition in children characterized by hypocalcemia and hyperphosphatemia due to defective synthesis /secretion of parathyroid hormone (PTH), end organ resistance or an inappropriately activated calcium-sensing receptor (CaSR). Clinical symptoms include muscle spasms, stridor, seizures, and syncope. It is rare for a child with this condition to present with cardiac failure at diagnosis. The therapeutic approaches...

ea0095oc2.2 | Oral Communications 2 | BSPED2023

Conquering the Storm: Surgical Intervention Rescues an Adolescent girl with Severe Thyrotoxicosis Refractory to Medical Management

Mehta Sajili , Ramya Gokul Pon , Ankur Raj , Lau Katherine , Park Julie , Dharmaraj Poonam

Introduction: GravesÂ’ disease (GD), although the most common cause of hyperthyroidism, is relatively uncommon in children, usually manifesting insidiously. Thyroid storm is a well described but rarely seen phenomenon in childhood GD; thyrotoxic crisis is less often discussed and its management can be challenging. We describe a case of GD with thyrotoxic crisis.Case: A 14-year-old female, known to have inadequately c...

ea0085oc5.9 | Oral Communications 5 | BSPED2022

Evaluation of a low postnatal hypoglycaemia threshold

Worth Chris , Ramya Gokul Pon , R Hashim , H Porte , Worthington Sarah , Dunne Mark , Estebanez Maria Salomon , A Mahaveer , Banerjee Indi

Background and objective: Neonatal hypoglycemia is common and frequently self-resolving, although rare due to congenital hyperinsulinism are associated with high risk of brain injury. The time period for neonatal hypoglycemia has been described in several studies. It is unknown if low hypoglycemia thresholds (<2.0 mmol/l) lead to missed cases of persistent hypoglycaemia. We aimed to ascertain if lower hypoglycemia threshold risked missing persistent forms of hypoglycemia i...

ea0095oc10.1 | Oral Communications 10 | BSPED2023

The real-world experience of long acting growth hormone in children with growth hormone deficiency

Ramya Gokul Pon , Jarvis Charlotte , Laing Peter , Das Urmi , Ramakrishnan Renuka , Dharmaraj Poonam , Blair Jo , Didi Mohammed , Senniappan Senthil

Introduction: Long-acting growth hormone (LaGH) therapy has emerged as a newer treatment option for children, with the potential to improve adherence and compliance. Clinical trials have shown LaGH formulations to be effective and safe in children with GH deficiency (GHD). Somatrogon (Ngenla) is licensed for use in children with GHD over than 3 years of age.Objective: We report the real-world experience of using once wee...