Endocrine Abstracts

Background: Patient information leaflets are widely used by clinicians to reinforce and supplement information discussed during a consultation. This helps empower the patient and their family by enabling them to gain a greater understanding about their condition, investigation and/or treatment. However, despite the global increase in digital activity leaflets are still being disseminated in printed form. Accessing them online may be the more preferable option and would also mo...

Introduction: Hybrid closed loop pumps (HCL) incorporate insulin pumps (IPs) with continuous glucose monitoring (CGM). Basal and bolus insulin release can be algorithmically adjusted in real-time enabling some automated insulin changes between meals according to set parameters. We reviewed the glycaemic control of patients with T1D cared for at the Evelina who had upgraded from IP to HCL between October 2020 and January 2022.Methods: As per standard care...

Introduction: Glucocorticoids can cause adrenal insufficiency through suppression of the hypothalamic-pituitary adrenal axis. Consensus on optimal glucocorticoid weaning or timing for dynamic function testing is lackingObjective: To investigate factors affecting short synacthen test (SST) response following high-dose corticosteroid therapy in children.Methods: This retrospective cohort study reviewed 17 patients referred to Evelina...

Introduction: Hybrid closed loop pumps (HCL) incorporate insulin pumps (IP) with continuous glucose monitoring (CGM). We reviewed the glycaemic control of patients with Type 1 Diabetes(T1D) cared for at the Evelina who had upgraded from basal bolus regimen or IP to HCL between October 2020 and March 2024.Method: As per standard care, patients were reviewed in clinic every 3 months and HbA1c was measured, and time in range (TIR) reviewed using CGM data.</...

Introduction: In recent years there has been a highlight on the inequity of diabetes care and results across the UK. Research needs to be taken into barriers of access to technology for type 1 diabetes in CYP in the UK, specifically looking at provider bias, systemic issues within the health system, and individual and family factors.Aim of the study: We explored the potential factors that might affect access to technolog...

Background: Achondroplasia, the most common skeletal dysplasia, carries a highest risk of developing foramen magnum stenosis (FMS), particularly in young children, leading to cervicomedullary compression and potentially fatal outcomes. Early detection of spinal cord changes through routine MRI screening can help reducing the morbidity and mortality in this population. Considering recent evidence, the bone team at Evelina London Children’s Hospital impleme...

Adrenal insufficiency (AI) is characterised by lack of cortisol production from the adrenal glands which is treated with replacement doses of hydrocortisone. At times of physiological stress there is an increased requirement for exogenous glucocorticoids, which if untreated can lead to an adrenal crisis. Currently there are no unified guidelines for those <18 years old in the UK; this can lead to a substantial variation in the management of AI in both an emergency and peri...