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Introduction: Congenital adrenal hyperplasia (CAH) is an autosomal recessively inherited disorder resulting from the mutations of one of Seven genes involved in adrenal steroidogenesis. The consequent enzyme defects lead to defects of varying severity of steroid biosynthesis. Patients require lifelong substitution treatment and endocrine care.Objectives: One of the many consequences of CAH is reduced fertility. The aim of this study was to investigate th...

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ea0070aep84 | Adrenal and Cardiovascular Endocrinology | ECE2020

Prognostic factors and overall survival in patients with adrenocortical cancer: Experiences of a single tertiary referral endocrine centre in Hungary (1974–2019)

Tőke Judit , Reismann Péter , Jakab Zsuzsanna , Micsik Tamás , Doros Attila , Kiss Róbert , Szücs Nikolette , Sármán Beatrix , Pusztai Péter , Nagy Géza , Horányi János , Szlávik Rezső , Huszty Gergely , Piros László , Lohinszky Júlia , Borka Katalin , Laki András , Varga Zsolt , Sápi Zoltán , Igaz Péter , Tóth Miklós

Introduction: Adrenocortical cancer is a rare malignant tumour with a poor prognosis. The incidence is 0.7–2.0/million/year.Objectives: The aim of this study was to characterise the clinicopathological features and prognostic factors of a large cohort of patients with adrenocortical cancer diagnosed between 1974–2019.Patients and Methods: The study included eighty patients (22 men and 58 women) with histologically confi...

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Endocrine Abstracts

Fertility testing in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Prognostic factors and overall survival in patients with adrenocortical cancer: Experiences of a single tertiary referral endocrine centre in Hungary (1974–2019)

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