Searchable abstracts of presentations at key conferences in endocrinology

ea0063p58 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

A case of Von Hippel-Lindau disease with bilateral pheochromocytoma and ectopic hypersecretion of intact parathyroid hormone

Bennour Marwa , Oueslati Ibtissem , Rejeb Ons , Mekni Sabrine , Yazidi Meriem , Grira Wafa , Chaker Fatma , Chihaoui Melika

Introduction: Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited syndrome predisposing to a variety of highly vascularised tumors in different organs. Although bilateral pheochromocytoma was reported in patient with VHL disease, the coexistence of primary hyperparathyroidism is not a common condition. Herein we report a case of a primary hyperparathyroidism secondary to an ectopic secretion of intact parathyroid hormone (PTH) in a patient with VHL disease and b...

ea0063p120 | Calcium and Bone 1 | ECE2019

A case of primary hyperparathyroidism in a patient with Lobstein’s disease

Mekni Sabrine , Oueslati Ibtissem , Grira Wafa , Rejeb Ons , Yazidi Meriem , Chaker Fatma , Chihaoui Melika

Introduction: Osteogenesis imperfecta also known as Lobstein’s disease (LD) is a rare disorder of type 1 collagen characterized by an increased susceptibility to bone fractures. Its coexistencewith primary hyperparathyroidism (PHP) was rarely described. Herein we report a new case of a primary hyperparathyroidismin a patient with a history of Lobstein’s disease.Observation: A 35-year-old woman was referred to our departmentfor hypercalcemia. He...

ea0063p363 | Thyroid 1 | ECE2019

Analysis of clinical and biological predictors of malignancy in thyroid nodules

Belaid Rym , Oueslati Ibtissem , Chaker Fatma , Rejeb Ons , Grira Wafa , Yazidi Meriem , Chihaoui Melika

Background: Thyroid nodules are the most common thyroid disease. In the majority of cases, they are benign. However, 5 to 15% of nodules are cancer. The aim of our study was to determine the clinical and biological predictive factors of malignancy in thyroid nodules.Methods: We performed a retrospective descriptive study including 100 patients collected in the endocrinology department of La Rabta hospital over 18 year old period (2000–2018). All the...

ea0063p364 | Thyroid 1 | ECE2019

Sensitivity and specificity of ultrasound features in predicting malignant thyroid nodules

Belaid Rym , Oueslati Ibtissem , Grira Wafa , Rejeb Ons , Yazidi Meriem , Chaker Fatma , Chihaoui Melika

Background: Ultrasound is valuable for identifying many malignant or potentially malignant thyroid nodules. The aim of this study was to evaluate the efficacy of ultrasonographic (US) features in predicting the malignancy of thyroid nodules in a group of Tunisian patients.Methods: We conducted a retrospective descriptive study including 100 patients collected in the endocrinology department of La Rabta hospital. All these patients underwent thyroidectomy...

ea0063p770 | Thyroid 2 | ECE2019

Voluminous multinodular goiter revealing an isolated thyrotropin deficiency

Mekni Sabrine , Oueslati Ibtissem , Rejeb Ons , Bennour Marwa , Grira Wafa , Yazidi Meriem , Chaker Fatma , Chihaoui Melika

Introduction: The goiter represents the most common of all the disorders of the thyroid gland. Many Factors may be involved in the evolution of multinodular goiter. Although thyroid stimulating hormone (TSH) was described as the most important goitrogen factor, impairment of TRH-induced TSH release was reported with nodular goiter, suggesting thyroid autonomy. Herein, we report two cases of an isolated thyrotropin deficiency in patient presented with a voluminous goiter.<p...

ea0049ep207 | Pituitary - Clinical | ECE2017

The risk of hypotension, evaluated by ambulatory blood pressure monitoring, during fasting and outside fasting in patients with adrenal insufficiency

Chihaoui Melika , Grira Wafa , Yazidi Meriem , Rejeb Ons , Chaker Fatma , Oueslati Ibtissem , Bettaieb Jihane , Slimane Hedia

The risk of hypotension during Ramadan fasting in patients with adrenal insufficiency is unknown. The aim of our study was to evaluate objectively this risk.Methods: It is a prospective case-crossover study on 28 patients with known and treated AI. Patients had no hypertension and were regular fasters. All patients underwent a clinical examination and a 24-hours blood pressure monitoring during Ramadan fasting then outside fasting....

ea0049ep570 | Diabetes complications | ECE2017

Risk factors of diabetic foot complications

Gharbi Radhouane , Chihaoui Melika , Rejeb Ons , Yazidi Meriem , Oueslati Ibtissem , Chaker Fatma , Slimane Hedia

Introduction: Diabetic foot disease is a major health problem. The identification of its risk factors should guide preventive measures. The aim of this study was to determine the factors associated with diabetic foot complications.Patients and methods: It is a retrospective study including 47 patients admitted at the department of Endocrinology in La Rabta hospital for diabetic foot complications during the years 2015 and 2016. Clinical and para-clinical...

ea0049ep1212 | Clinical case reports - Thyroid/Others | ECE2017

Atrial flutter with 1:1 atrioventricular conduction: An uncommon cardiac manifestation of hyperthyroidism

Rached Amal , Yazidi Mariem , Sakka Imen , Rejeb Ons , Khessairi Nedia , Chihaoui Malika , Slimane Hedia

Introduction: Atrial flutter (AFL) is a rapid, regular atrial tachyarrhythmia that occurs most commonly in patients with underlying structural heart disease. Patients with tachyarrythmias as a result of thyroid storm have been typically treated with beta-blockers to decrease the heart rate and alleviate beta-receptor mediated symptoms. We report an unusual case of AFL with 1:1 atrioventricular (AV) conduction.Case report: Patient H, M 45 years old was ad...

ea0049ep1322 | Thyroid (non-cancer) | ECE2017

Cardiothyreosis: prevalence and risk factors

Yazidi Meriem , Chihaoui Melika , Oueslati Hiba , Rejeb Ons , Ouali Sana , Rejaibi Salsabil , Chaker Fatma , Slimane Hedia

Background: Cardiothyreosis (CT) or thyrotoxic heart is associated with higher morbidity and mortality than the other forms of hyperthyroidism. Its risk factors have been investigated in a limited number of studies. The aim of our study was to identify risk factors of CT in patients with hyperthyroidism.Methods: We identified 538 patients with a hospital discharge diagnosis of hyperthyroidism from January 2000 to December 2015. Thirty five patients were ...

ea0049ep1324 | Thyroid (non-cancer) | ECE2017

Therapeutic and evolutionary characteristics of subclinical hypothyroidism

Yazidi Meriem , Mezghani Imed , Chaker Fatma , Rejeb Ons , Chihaoui Melika , Slimane Hedia

Subclinical hypothyroidism (SCH) is a common disorder and indications of treatment are still being debated. The aim of our study was to describe the therapeutic and evolutionary characteristics of SCH.Methods: We undertook a longitudinal retrospective study in 110 patients with SCH biologically defined by increased serum thyroid-stimulating hormone (TSH) levels (>4 mIU/l) and normal FT4. Pregnancy, age less than 18 years, personal history of partial ...