Searchable abstracts of presentations at key conferences in endocrinology

ea0081p481 | Thyroid | ECE2022

Unexpected alterations in thyroid status: a case of alemtuzumab-induced Graves’ disease with fluctuating course

Filipa Araujo Barbara , Lavrador Mariana , Araujo Catia , Ribeiro Ana , Paiva Sandra , Paiva Isabel

Introduction: Alemtuzumab is a humanized anti-CD52 monoclonal antibody approved for the treatment of relapsing−remitting multiple sclerosis (RRMS). Through an immune reconstitution mechanism, it leads to thyroid autoimmunity in 35% of cases, with Graves’ disease (GD) being the most common presentation. Alemtuzumab-induced GD exhibits distinctive clinical and immunological features, with rarely reported cases of fluctuating thyroid status with documented both blockin...

ea0090p135 | Pituitary and Neuroendocrinology | ECE2023

Prolactinomas under high doses cabergoline in portuguese patients: The Resistant Prolactinoma Study

Manique Ines , Benido Silva Vania , Carvalho Davide , Marques Olinda , Nobre Ema , Joao Bugalho Maria , Palha Ana , Ribeiro Isabel , Pereira Josue , Almeida Rui , Sagarribay Amets , Cerqueira Luis , Amaral Claudia

Background: In 15% of prolactinomas there is dopamine agonist(DA) resistance. The clinical characteristics, the best diagnostic and therapeutic management of these cases have not been established so far.Aim: To characterize patients taking a high dose cabergoline(≥ 3mg/week) and then describe clinical, biochemical and imaging features of cabergoline-resistant cases.Methods: Retrospective study with 5 centers representing the ...

ea0073aep756 | Thyroid | ECE2021

Papillary thyroid cancer presenting with splenic infarction

Saraiva Miguel , Magda Garça , Rita Costa Ana , Pinheiro Guiomar , Rita Cruz Ana , Ribeiro Sofia , Cláudia Freitas , André Carvalho

IntroductionThe close relationship between cancer and thrombotic phenomena has been widely recognized and paraneoplastic organ infarctions may occur. Reports of papillary thyroid cancer associated to paraneoplastic phenomena are particularly scarce.Case reportA 39-year-old man with no prior relevant medical history was evaluated for acute onset of fever, malaise and mild pain referred to his left hypochondriu...