Endocrine Abstracts

Section 1: Case history: A 55 year woman presented with a one month history of fatigue, anxiety, tremor and diarrhoea. She was diagnosed with Grave’s thyrotoxicosis and commenced on Carbimazole 30 mg daily. Thyroid hormones normalised, but after three weeks of therapy she developed rapidly progressive ascending numbness and weakness predominantly affecting her legs. Examination revealed distal symmetrical lower motor neurone weakness and widespread loss of light touch sensatio...

A 35 year old Asian man presented to the emergency department on several occasions with episodes of severe muscle weakness, affecting his arms and legs, to the point he was unable to walk or stand. He was found to be hypokalaemic on both occasions, at 2.3mmol/l and 3.0mmol/l respectively, and his weakness gradually improved with potassium replacement. He gave a history of two years of intermittent weakness and stiffness of the limbs which typically occurred at night or after l...

A 51-year-old man presented to an optometrist with a 3-week history of visual impairment following a minor headache. He was found to have reduced visual acuity 6/24 in both eyes and a dense bitemporal hemianopia and was referred urgently to Musgrove Park Emergency Department. MRI brain showed a cystic bleed from a pituitary macroadenoma, 30 mm in diameter, with compression of the optic chiasm. He had no clinical features of Cushing’s or other hormone excess or deficiency ...