Searchable abstracts of presentations at key conferences in endocrinology

ea0011p268 | Diabetes, metabolism and cardiovascular | ECE2006

Increased expression of the adipokines resistin and fiaf in hypoxic/ischemic mouse brain

Wiesner G , Brown RE , Robertson GS , Ur E , Wilkinson M

Obesity and adipokines are associated with a state of chronic low grade inflammation (Trayhurn & Wood 2004).In view of our findings that the adipokines resistin and fiaf (fasting-induced adipose factor) are also expressed in mouse brain and pituitary gland (Wiesner et al 2004), we tested the hypothesis that these factors would be induced in brain tissue following cerebral hypoxia/ischemia (H/I). Neonatal H/I (postnatal day 8; unilateral common c...