Searchable abstracts of presentations at key conferences in endocrinology

ea0011s36 | Clinical lessons from novel aspects of G protein-coupled receptors signalling | ECE2006

Moleular pathology of the FSH receptor

Vasseur C , Rodien P , Meduri G , Touraine P , Lahuna O , Kuttenn F , Misrahi M

The identification of naturally occurring genetic mutations of the FSH receptor has led to a better understanding of the role of FSH in folliculogenesis and has allowed to identify the cause of several syndroms. Inactivating mutations of the follicle stimulating hormone (FSH) receptor have been described in rare cases of premature ovarian failure (POF). We have studied a new patient presenting a complete POF phenotype, with high plasma FSH levels, very low estrogen and inhibin...

ea0011p841 | Thyroid | ECE2006

Levothyroxine suppressive therapy and body composition

Dubois-Ginouves S , Laboureau-Soares Barbosa S , Dumas JF , Abraham P , Sallé A , Illouz F , Rodien P , Ritz P , Rohmer V

Reputedly, thyroid hormones make thinner and change the body composition. The aim of this randomized and prospective study was the assessment of the effect of levothyroxine suppressive therapy on body composition in women with benign thyroid nodule.Method: Thirty seven euthyroid and non obese women (18–60 years old) with benign thyroid nodule (fine needle cytology and calcitonin measurement) were randomized into 2 equal groups. The first group recei...

ea0029p1786 | Thyroid cancer | ICEECE2012

Is thyroid cancer recurrence risk increased after transplantation?

Tisset H. , Kamar N. , Faugeron I. , Pouteil-Noble C. , Klein M. , Frimat L. , Mourad G. , Drui D. , Do Cao C. , Vanthygem M. , Noel C. , Leenhardt L. , Rodien P. , Bonichon F. , Morelon E. , Leboulleux S. , Bournaud C. , Kelly A. , Niccoli P. , Schlumberger M. , Borson-Chazot F.

Context: An increased mortality by cancer is reported in grafted patients.Objective: This multicentric study aimed to investigate whether the prognosis of thyroid cancer was modified by transplantationResults: Sixty nine patients (35 M/34 F; median age 41 years) with a history of both thyroid cancer and transplantation were recruited via specialized networks (TUTHYREF and DIVAT). Evolution and outcome were retrospectively analyzed ...