ea0016p673 | Steroid receptors | ECE2008
van Etten Evelyne
, Verlinden Lieve
, Giulietti Annapaula
, Lopez Elizabeth Ramon
, Branisteanu Dumitru D
, Ferreira Gabriela Bomfim
, Overbergh Lutgaard
, Verstuyf Annemieke
, Bouillon Roger
, Roep Bart O
, Badenhoop Klaus
, Mathieu Chantal
1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) influences the differentiation and cytokine secretion of various immune cell types. These immune modulating effects of 1,25(OH)2D3 are mediated through the nuclear vitamin D receptor (VDR). In the immune system, the 1,25(OH)2D3/VDR complex interacts with promoter vitamin D responsive elements (VDRE), or interferes with the signalling of other transcription factor...