Searchable abstracts of presentations at key conferences in endocrinology

ea0029p814 | Endocrine tumours and neoplasia | ICEECE2012

Efficacy of Everolimus to prevent hypoglycemia in patients with metastatic insulinomas: for the French group of endocrine tumors (GTE-Renaten)

Bernard V. , Lombard-Bohas C. , Goichot B. , Rohmer V. , Guimbaud R. , Niccoli P. , Chougnet C. , Ruszniewski P. , Baudin E.

Background: Refractory hypoglycemia in patients with metastatic insulinomas (RHMI) is an important cause of morbidity and mortality and everolimus could be a new therapeutic option.Methods: We conducted a restrospective multicentric study within the French group of endocrine tumors to evaluate the time to first symptomatic recurrence (TSR) in patients with RHMI after everolimus initiation. Ongoing hyperglycemic medical options and safety were recorded.</...

ea0011p841 | Thyroid | ECE2006

Levothyroxine suppressive therapy and body composition

Dubois-Ginouves S , Laboureau-Soares Barbosa S , Dumas JF , Abraham P , Sallé A , Illouz F , Rodien P , Ritz P , Rohmer V

Reputedly, thyroid hormones make thinner and change the body composition. The aim of this randomized and prospective study was the assessment of the effect of levothyroxine suppressive therapy on body composition in women with benign thyroid nodule.Method: Thirty seven euthyroid and non obese women (18–60 years old) with benign thyroid nodule (fine needle cytology and calcitonin measurement) were randomized into 2 equal groups. The first group recei...

ea0029p993 | Growth hormone IGF axis - basic | ICEECE2012

Clinical characteristics and outcome of acromegaly induced by ectopic secretion of GHRH: a French nationwide series of 21 cases

Garby L. , Caron P. , Claustrat F. , Chanson P. , Tabarin A. , Rohmer V. , Arnault G. , Bonnet F. , Chabre O. , Christin Maitre S. , Du Boullay H. , Murat A. , Nakib I. , Sadoul J. , Sassolas G. , Claustrat B. , Raverot G. , Borson Chazot F.

Context: Ectopic GHRH secretion is a rare cause of acromegaly described mainly in isolated case reports.Setting: From the registry of the sole laboratory performing plasma GHRH assays in France, we identified cases of ectopic GHRH secretion presenting with acromegaly between 1983 and 2008.Patients: In total, 21 patients aged 14–77 years, from 12 French hospitals. Median GHRH was 548 ng/l (270–9779)....

ea0026p70 | Endocrine tumours and neoplasia | ECE2011

First prognostic analysis of stage III adrenocartical carcinoma patients after complete resection: a retrospective French Multicentric Study from the INCA-COMETE network

Do Cao C , Leboulleux S , Borget I , Bertherat J , De la Fouchardiere C , Hecart A C , Caron P , Tabarin A , Niccoli P , Rohmer V , Drui D , Schillo F , Raingeard I , Young J , Ghuzlan A , Borson-Chazot F , Bertagna X , Pattou F , Wemeau J L , Francis Z , Libe R , Aubert S , Baudin E

Objective: To assess outcome of stage III–ENSAT adrenocortical carcinoma (ACC) patients after complete macroscopic resection and prognostic factors for disease-free survival (DFS) and overall survival (OS).Methods: A retrospective review of 68 stage III ACC patients treated surgically between 1994 and 2009 in the French COMETE network was performed. Characteristics of patients were reviewed by a single investigator as well as the Weiss score by expe...