Searchable abstracts of presentations at key conferences in endocrinology

ea0063p116 | Calcium and Bone 1 | ECE2019

Successful removal of parathyroid cancer metastasis from VI thoracic vertebra

Mokrysheva Natalia , Krupinova Julia , Gorbacheva Anna , Teplyakov Valeriy , Rumyantsev Pavel

Background: Approximately 25% of patients with parathyroid carcinoma (PC) have metastases; the most frequent sites include cervical lymph nodes (30%) and lungs (40%). Less common are liver, bones and brain. Surgical resection of local or distant metastases (if possible) provides the best control of hypercalcemia and enhances long-term survival.Case description: A 70-year old patient was admitted to hospital with a primary hyperparathyroidism (PH). He did...

ea0063p423 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

Comparison of visualization methods in ACTH-ectopic lung tumor: a case report

Petrushkina Alexandra , Pigarova Ekaterina , Dzeranova Larisa , Rumyantsev Pavel , Slaschuk Konstantin , Sheremeta Marina , Melnichenko Galina

Background: ACTH-ectopic syndrome is a rare cause of endogenous hypercortisolism and may pose serious difficulties in topical diagnosis.Case description: Clinical features of hypercortisolism manifested at the age of 18 years (2012). A year later he was referred to an endocrinologist: ACTH 113 pg/ml (0–46), cortisol in 24-h urine 2915 μg/day (4.3–176), 1 mg DX test cortisol 1020 nmol/l, 8 mg DX test 764 nmol/l, intact pituitary MRI with co...

ea0070ep463 | Thyroid | ECE2020

Radioiodine therapy outcome in patient with toxicmultinodular goiter with concomitant hereditary hasharon hemoglobinopathy

Dzeytova Dali , SHklyaev Stanislav , Rumyantsev Pavel , Sheremeta Marina , Trukhin Alexey , Cvetaeva Nina , kozhedub Evgenij

Aim/introduction: The main purpose of this work was to describe a clinical case of thyrotoxicosis with concomitant HASHARON hemoglobinopathy scrutinizing whether the latter could hinder radioiodine therapy (RIT).Materials and methods: Patient H., 53 years old, diagnosed with moderate toxic diffuse multinodular goiter. Clinical manifestation of the disease were in summer 2018 (TSH – 0 mIU/ml). Medication with thyrozole (20 mg) was initiated. Thyroto...

ea0063p82 | Calcium and Bone 1 | ECE2019

A case report of tumor-induced osteomalacia

Zhukov Artem , Pigarova Ekaterina , Petrushkina Alexandra , Rozhinskaya Liudmila , Beltsevich Dmitry , Slashuk Konstantin , Rumyantsev Pavel , Kogan Evgeniya , Osmanov Yusif , Melnichenko Galina

Objective: Tumor-induced osteomalacia is a rare paraneoplastic syndrome in which fibroblast growth factor 23 (FGF-23) hyperproduction by tumor causes renal phosphate wasting, severe hypophosphatemia and osteomalacia. Localization of the tumor can be a major diagnostic challenge.Material and methods: We present a clinical case concerning a 62-year old woman previously diagnosed with hypophosphatemic osteomalacia, with a slight improvement of clinical and ...

ea0056p1134 | Thyroid cancer | ECE2018

The relationship between clinical, morphological and prognostic characteristics of papillary thyroid carcinoma with BRAFV600E mutation assessed immunohistochemically

Sidorin Aleksei , Abrosimov Aleksandr , Rogounovitch Tatiana , Rumyantsev Pavel , Nizhegorodova Kseniya , Isaev Pavel , Shinkarkina Anna , Yamashita Shunichi , Saenko Vladimir

Background: Papillary thyroid carcinoma (PTC), especially its classic papillary, oncocytic, Warthin-like, tall and columnar cell variants, is characterized by a high frequency of BRAFV600E mutation that varies in different studies from 36 to 85%. Prognostic significance of the mutation remains controversial.Objective: Aim of the study was an analysis of relationship between clinical, morphological and prognostic characteristics of PTC with BRAFV600E asse...