Searchable abstracts of presentations at key conferences in endocrinology

ea0038p389 | Steroids | SFEBES2015

Regulation of glucocorticoid receptor action by ARID subunits of the SWI/SNF complex

Russell Felicity Ellen , Conway-Campbell Becky L , Birnie Matthew , Biddie Simon , Lightman Stafford

AT-rich interacting domain (ARID) subunits can interact with the glucocorticoid receptor (GR) and therefore may be essential for gene transcription dependent on receptor signalling. Glucocorticoids are steroid hormones important for regulating a variety of physiological processes through the binding and activation of GR. GR associates with numerous co-regulators, such as chromatin remodelling factors, to mediate gene induction or repression. One chromatin remodelling complex w...