Searchable abstracts of presentations at key conferences in endocrinology

ea0010p83 | Steroids to include Cushing's | SFE2005

A proliferative role for liver X receptors within human skin

Russell L , Philpott M , Burrin J

Liver X receptors α and β (NR1H3 and NR1H2) play major a role within cells and tissues involved in lipid metabolism and cholesterol homeostasis including macrophages, the liver and the small intestine. Within the skin however, the roles of LXR are less well documented, although in vitro studies using primary human keratinocytes have implemented LXR in the formation of the stratum corneum via the increase of transcription of the proteins involved in the AP-1 co...

ea0005p55 | Clinical Case Reports | BES2003

Growth hormone deficiency and pregnancy

Brackenridge A , Breen L , Russell-Jones D

It is recognised that growth hormone deficiency causes disturbances in reproductive function. Indeed growth hormone has been used for ovulation induction in the treatment of subfertility in women with hypopituitarism. During normal pregnancy growth hormone is produced by the placenta (placental growth hormone). From 15 to 20 weeks gestation placental growth hormone gradually replaces pituitary growth hormone in the maternal circulation and is the main determinant of maternal I...