Endocrine Abstracts

History: A 38-year-old Afghan lady was referred for investigation of secondary amenorrhoea. She had had no menstrual periods since her first spontaneous pregnancy, except when recently taking a combined oral contraceptive pill (COCP). When living abroad, she conceived on three further occasions with clomiphene induction, resulting in two live births and one miscarriage. In addition, it was noted that she had never been able to breast-feed any of her children. She did not have ...

Introduction: Cranial diabetes insipidus (DI) is a rare presenting complication of acute myeloid leukaemia (AML) or myelodysplasia, usually associated with complex cytogenetics. We report the case of a patient previously treated with cytotoxic therapy who presented with DI and AML. Case report: A 39 year old male presented with a three month history of lethargy, fatigue, and breathlessness. He also reported a ten day history of acute onset polydipsia and polyuria. He had been ...

Case history: A 64-year-old male was admitted to our hospital in January 2024 following a road traffic accident. The patient was not wearing a seatbelt, and airbags did not deploy due to low speed, resulting in the patient’s head hitting the windscreen. A subsequent CT trauma series showed a large destructive expansile lesion within the clivus and sphenoid bone extending superiorly into the hypothalamus with findings typical of a chordoma. Appearance on non-contrast MRI w...