Searchable abstracts of presentations at key conferences in endocrinology

ea0014p376 | (1) | ECE2007

Increase of L-thyroxine requirement during pregnancy

Russo Laura , Tonacchera Massimo , Gianetti Elena , Vitti Paolo , Pinchera Aldo

In pregnant women with a thyroid disease an increased amount of LT4 may be required for the correction of hypothyroidism or treatment of nodular goiter.Aim of this study was to assess the amount of the variations of LT4 requirement in pregnant women with thyroid diseases.To address this issue, we retrospectively evaluated a cohort of 138 women treated with LT4 divided in two groups: 47 euthyroid (E) (affected by nodular goiter (NG)...

ea0014p377 | (1) | ECE2007

Safety of pharmacological treatment of thyroid diseases &br;during pregnancy

Gianetti Elena , Tonacchera Massimo , Russo Laura , Vitti Paolo , Pinchera Aldo

Pregnant women may require treatment of hypo- or hyperthyroidism, L-thyroxine (LT4), propylthiouralcil (PTU) and methimazole (MMI) being the most frequently used drugs. Aim of this study was to verify the consequences of pharmacological treatment during pregnancy. We retrospectively evaluated 379 pregnancies: 124 patients under MMI treatment, 35 of whom still hyperthyroid in spite of treatment (H-MMI) and 89 euthyroid (E-MMI); 52 GD patients under PTU, 20 of whom still hyperth...