Endocrine Abstracts

Introduction: MAIT cells are a unique subset of T-cells, that have been conserved throughout 150 million years of mammalian evolution. They can contribute to rapid pathogen control, tissue repair and anti-cancer immunity, but can also cause inflammation and tissue damage in diseased settings. Previously, we have reported dysregulated peripheral blood MAIT cells in children and adults with obesity, highlighting altered cellular metabolism as the causative mechanism. However, th...