Searchable abstracts of presentations at key conferences in endocrinology

ea0014p16 | (1) | ECE2007

Changes in growth hormone messenger RNA (GHmRNA) expression in rats anterior pituitary after single Interferon (IFN)alpha administration.

Romanowski Wojciech , Braczkowski Ryszard , Danikiewicz Aleksander , Nowakowska-Zajdel Ewa , Muc-Wierzgon Malgorzata , Muryn Zuzanna , Zubelewicz-Szkodzinska Barbara

Introduction: Interferon alpha (IFN alpha) is a cytokine with pleiotropic effects and via different pathways influences secretion of certain cytokines and hormones. Growth Hormone (GH) secreted from the pituitary has its physiological effects on various target tissues. The question is how IFN alpha administered in various type of diseases influences GH secretion. This study investigated acute effect of IFN-alpha on GH mRNA expression in rat anterior pituitary<p class="abst...