Endocrine Abstracts

Multiple myeloma is a hematologic malignancy characterized by osteolytic bone destruction which follows the increased osteoclastic resorption of bone that is not accompanied by increased bone formation. This can lead to bone pain, diffuse osteopenia, focal lytic lesions, pathologic fractures, spinal cord compression, and hypercalcemia, so it is evident that osteolytic bone disease is a major cause of morbidity and mortality in patients with multiple myeloma. Long-term monthly ...

Hypothalamic-pituitary (HP) dysfunction is common in children treated with cranial radiotherapy (RT) for brain tumours but there is little known about the risk of HP dysfunction in adults treated with RT for primary non-pituitary brain tumours.We aimed to investigate the frequency of HP dysfunction in adults after RT for primary brain tumours which are distant from the HP region.We studied 56 adult patients who received external be...