Searchable abstracts of presentations at key conferences in endocrinology

ea0086p27 | Adrenal and Cardiovascular | SFEBES2022

Sulfasalazine as a cause of false positive elevation of normetanephrine in patients with adrenal mass – A diagnostic challenge

Ter Zuling Eunice , Balasubramanian Sabapathy

In clinical settings, when biochemical screening revealed grossly elevated urinary normetanephrine and metanephrine in the presence of an adrenal mass, there is a high clinical suspicion of a pheochromocytoma. However, sulfasalazine, an anti-inflammatory drug can cause analytical drug interference, leading to falsely positive elevation of urinary normetanephrine and a misdiagnosis of phantom pheochromocytoma. This report illustrates two patients with adrenal mass who had false...

ea0028p15 | Bone | SFEBES2012

Unusual presentation of primary hyperparathyroidism

Shillo Pallai Rappai , Balasubramanian Sabapathy

An 80 year old patient was diagnosed with asymptomatic, mild primary hyperparathyroidism in 2005 and managed conservatively with regular biochemical monitoring. Other medical history included atrial fibrillation, hypertension, CKD stage 3, type 2 diabetes and memory impairment. In 2011, in view of increasing calcium, he was referred to the endocrine surgeons to consider parathyroidectomy. A very low 25 (OH)vit D (12 nmol/L) prompted high dose oral cholecalciferol treatment. Th...

ea0086p10 | Adrenal and Cardiovascular | SFEBES2022

Practices in perioperative management of patients with pheochromocytoma and paraganglioma: a Scoping Review

Bojoga Andreea , Narula Harveer , Balasubramanian Sabapathy

Introduction: There is variation in practice with regards to preoperative optimization protocols and postoperative management in pheocromocytoma and related paraganglioma (PPGL). We aimed to review the literature on perioperative strategies to reduce morbidity and mortality following surgery for PPGL and enhance understanding of optimal approaches.Methods: Two databases were systematically searched in January 2020 for terms related to perioperative manag...

ea0031p70 | Clinical practice/governance and case reports | SFEBES2013

Normal plasma and urine catecholamines in a patient with symptoms and radiological findings of a phaeochromocytoma cured by laparoscopic adrenalectomy

Elhassan Yasir Mohamed , Ross Richard , Balasubramanian Sabapathy

A 60-year-old woman was referred with a 14 mm right adrenal mass on a contrast CT abdomen whilst being investigated for left iliac fossa pain and increased bowel frequency. She reported a 2-year history of anxiety attacks, poor sleep, excessive sweating and weight loss. She had hypertension, asthma and recurrent vasovagal syncope and had previously undergone an open cholecystectomy. Her medications included Lansoprazole, Salbutamol, Losartan, Citalopram and Diltiazem. Systemic...

ea0086p285 | Thyroid | SFEBES2022

Preoperative Rapid Optimisation in poorly controlled Graves’ disease: An outpatient experience during the COVID-19 pandemic

Shaan Goonoo Mohummad , Fahad Arshad Muhammad , Hussein Ziad , Balasubramanian Sabapathy

Background: Traditional method in Sheffield involved preoperative admission and use of an intensive regimen. The pandemic led to the development and implementation of an outpatient-based protocol (SPROG - ‘Sheffield Peri-operative Rapid Optimisation in Graves’ disease (GD)’) for patients’ intolerant to thionamides and/or with uncontrolled disease requiring thyroidectomy. Control was achieved using sequential addition and dose-escalation of drugs such as Lug...

ea0044ep4 | (1) | SFEBES2016

Failure to suppress TSH in thyroid cancer – could it be Addison’s disease?

Fowler George E , Wadsley Jonathan , Webster Jonathan , Balasubramanian Sabapathy P

Background: Papillary thyroid cancer is the commonest thyroid malignancy. Surgery is first-line treatment, followed by radioiodine and long-term, high dose levothyroxine to suppress TSH.Cortisol is known to suppress TSH secretion by the pituitary, although the mechanism remains unclear. Correspondingly, hypocortisolism may raise TSH levels.Case Summary: A 64 year old woman presented with a right-sided thyroid nodule, normal TSH and...